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Taxonomic group: bacteria / Firmicutes (Phylum: Firmicutes)
Associated disease: pneumonia [ICD11: CA40

]; infection due to Streptococcus pneumoniae [ICD11: XN3PW

]

The structure was elucidated in this paper
NCBI PubMed ID: 20217879
Journal NLM ID: 0370543
Publisher: Weinheim: Wiley-VCH
Correspondence: richard.schmidt

uni-konstanz.de
Institutions: Fachbereich Chemie, Universitat Konstanz, Fach 725, 78457 Konstanz, Germany

Streptococcus pneumoniae, lipoteichoic acid, chemical synthesis

Structure type: oligomer
Location inside paper: p.2589, scheme 6, 1a
Trivial name: lipoteichoic acid (LTA)
Contained glycoepitopes: IEDB_114703,IEDB_115009,IEDB_116046,IEDB_130648,IEDB_137473,IEDB_1391961,IEDB_140624,IEDB_141109,IEDB_141582,IEDB_141584,IEDB_142345,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_153207,IEDB_176772,IEDB_241118,IEDB_885822,IEDB_983931,SB_192

Methods: 13C NMR, 1H NMR, chemical synthesis
Biological activity: the induction of innate immune responces
Synthetic data: chemical

NCBI Taxonomy refs (TaxIDs): 1313
Show glycosyltransferases

There is only one chemically distinct structure:

CCCCCCCCCCCCCC(=O)OC[C@@H](CO[C@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](C)[C@H](N)[C@H](O[C@@H]3O[C@H](COP(=O)(O)OC[C@H](O)[C@H](O)[C@H](O)CO[C@@H]4O[C@H](COP(=O)(O)OCC[N+](C)(C)C)[C@H](O)[C@H](O[C@H]5O[C@H](COP(=O)(O)OCC[N+](C)(C)C)[C@H](O[C@H]6O[C@H](C)[C@H](N)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6NC(C)=O)[C@H](O)[C@H]5NC(C)=O)[C@H]4NC(C)=O)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCC

SVG MW SMILES 3D mol Ionize