Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Helicobacter pylori [ICD11:
XN3DY 
];
infection due to Campylobacter jejuni [ICD11:
XN4Q5 ]
NCBI PubMed ID: 19882127Publisher: Totowa, NJ: Humana Press
Editors: Holst O, Walker JM, Beck A
Institutions: Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario, Canada
Glycomics which is the study of saccharides and genes responsible for their formation requires the continuous development of rapid and sensitive methods for the identification of glycan structures. It involves glycoanalysis which relies upon the development of methods for determining the structure and interactions of carbohydrates. For the application of functional glycomics to microbial virulence, carbohydrates and their associated metabolic and carbohydrate processing enzymes and respective genes can be identified and exploited as targets for drug discovery, glyco-engineering, vaccine design, and detection and diagnosis of diseases. Glycomics also encompasses the detailed understanding of carbohydrate-protein interactions and this knowledge can be applied to research efforts focused toward the development of vaccines and immunological therapies to alleviate infectious diseases.
NMR, structural analysis, molecular modeling, polysaccharides, HR-MAS, Glycomics, glycans, glycoanalysis, protein–carbohydrate interactions
Structure type: monomer
Location inside paper: p.159, fig.11.4, 2
Trivial name: UDP-hexos-4-ulose sugar, UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose, UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hexos-4-ulose, UDP-2-acetamido-2,6-dideoxy-β-L-arabino-4-hexulose
Compound class: nucleoside diphosphate sugar
Methods: NMR
Enzymes that release or process the structure: PseB (C4,6-dehydratase/C5-epimerase)
Related record ID(s): 20218, 20535, 21190, 21963, 23110, 23133, 24189, 25192, 25543, 25545, 25546, 25547, 25548
NCBI Taxonomy refs (TaxIDs): 210,
197
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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