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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11: XN6P4

]

NCBI PubMed ID: 20618127
Publication DOI: 10.1134/S0006297910040012
Journal NLM ID: 0376536
Publisher: Nauka/Interperiodica
Correspondence: kabanovd1

rambler.ru
Institutions: Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Russia

This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.

core, Lipooligosaccharide, O-antigen, lipid A, gangliosides, cytokines, lipopolysaccharide (endotoxin)

Structure type: polymer biological repeating unit
Location inside paper: p.397, table 9
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_135813,IEDB_136045,IEDB_137340,IEDB_141807,IEDB_142489,IEDB_144562,IEDB_145669,IEDB_150092,IEDB_151531,IEDB_152214,IEDB_174333,IEDB_423096,SB_86

Comments, role: review; D configurations of common residues are from Ref [192].

Related record ID(s): 3161, 9411, 11788, 20692, 21741, 23067, 23214
NCBI Taxonomy refs (TaxIDs): 562
Reference(s) to other database(s): GTC:G59020TN, GlycomeDB:28129
Show glycosyltransferases

There is only one chemically distinct structure:

*O[C@H]1[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H](C(=O)O)O[C@H](O[C@H]3[C@H](O)[C@H](O[C@@H]4[C@@H](NC(C)=O)[C@H](*)O[C@H](CO)[C@H]4O)O[C@@H](C)[C@H]3O)[C@H](O)[C@H]2O)[C@@H]1NC(C)=O

SVG MW SMILES 3D mol Ionize