Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: bacillary dysentery (shigellosis) [ICD11:
1A02 
, ICD11:
SA56 
, ICD11:
XN7HG 
];
diarrhea [ICD11:
ME05.1 
, ICD11:
SA55 
];
infection due to Shigella flexneri [ICD11:
XN7Y2 
]
The structure was elucidated in this paperNCBI PubMed ID: 20644600Publication DOI: 10.1134/S1068162010030179Journal NLM ID: 7804941Publisher: Moskva: Nauka
Correspondence: annakond

gmail.com
Institutions: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
The full structure of the lipopolysaccharide core of bacteria Shigella flexneri types 2a and 5b, the causative agents of bacillary dysentery (shigellosis), was established by chemical methods, high-resolution electrospray ionization mass spectrometry, and two-dimensional NMR spectroscopy. The structure of the O-antigen repeating unit and the configuration and position of the linkage between the O-antigen and the core were determined in the lipopolysaccharide of S. flexneri type 2a.
Lipopolysaccharide, oligosaccharide, structure, O-antigen, Shigella flexneri
Structure type: polymer chemical repeating unit
Location inside paper: p.398, fig.2b
Trivial name: O-unit in the S-form LPS
Contained glycoepitopes: IEDB_135813,IEDB_137340,IEDB_1394181,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_145005,IEDB_145010,IEDB_146664,IEDB_151531,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, methylation, NMR-2D, ESI-ICR-MS, alkaline hydrolysis
Related record ID(s): 25311, 25722, 25723, 25724
NCBI Taxonomy refs (TaxIDs): 42897,
2021401Reference(s) to other database(s): GTC:G38657UI
Show glycosyltransferases
There is only one chemically distinct structure: