Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: plague [ICD11:
1B93 
, ICD11:
XN6QS ];
infection due to Yersinia pestis [ICD11:
XN6QS ]
Publication DOI: 10.1134/S1068162011040042Journal NLM ID: 9420101Publisher: Springer Science and Business Media
Correspondence: ovoys
physiol.komisc.ru
Institutions: Institute of Physiology, Komi Science Centre, the Urals Branch of the Russian Academy of Sciences, 50, Pervomaiskaya str., Syktyvkar, 167982 Russia
The immunobiological properties of plague microbe antigens are described in the review. All of the identified antigens are evaluated in relation to the pathogenicity of Yersinia pestis (resistance to phagocytosis, toxicity, adhesiveness, etc.), as well as persistence ability and adaptation to a variable environment. In addition, the role of the antigen in the immunogenicity of a living plague microbe and literature data about the inherent protectiveness of antigens for the model animals are discussed. The data concerning the mechanisms of antigenic contribution to the development of the adaptive immunity are presented.
antigen, pathogenicity, immunity, Yersinia pestis, protectiveness
Structure type: oligomer
Location inside paper: p.405
Aglycon: lipid A
Compound class: core oligosaccharide, LPS
Contained glycoepitopes: IEDB_130650,IEDB_130659,IEDB_130670,IEDB_135607,IEDB_135609,IEDB_135813,IEDB_136044,IEDB_137340,IEDB_137472,IEDB_140087,IEDB_140088,IEDB_140090,IEDB_141794,IEDB_141807,IEDB_142488,IEDB_146664,IEDB_151531,IEDB_190606,IEDB_2189046,IEDB_2189047,IEDB_226811,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88
Methods: NMR, sugar analysis, MS
Comments, role: review
NCBI Taxonomy refs (TaxIDs): 632
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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