Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 21074753Publication DOI: 10.1016/j.carres.2010.10.012Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: E. Vinogradov <Evguenii.Vinogradov
nrc-cnrc.gc.ca>
Institutions: National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, USA
Recently it was demonstrated that Shigella dysenteriae type 1, a cause of severe dysentery epidemics, gained its O-specific polysaccharide (O-SP) from Escherichia coli O148. The O-SPs of these bacteria differ only by a galactose residue in the repeat unit of S. dysenteriae type 1 in place of a glucose residue in E. coli O148. Herein, we analyzed the core structure and its linkage to the O-SP in E. coli O148 LPS. Both were found to be identical to those of S. dysenteriae type 1 structures, further supporting the relatedness of these two bacteria. The following structure of the core with one repeat unit of the O-SP has been assigned (all have d-configuration except l-Rha): (formula: see text).
LPS, structure, core, O-specific polysaccharide, Escherichia coli O148
Structure type: suggested polymer biological repeating unit
Location inside paper: p.151, fig.1 RU
Aglycon: core ID 26855
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_136105,IEDB_137340,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_225177,IEDB_885823,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, sugar analysis, 31P NMR, ESI-MS, mild acid hydrolysis
Related record ID(s): 11572, 21578, 23062, 26855, 27289
NCBI Taxonomy refs (TaxIDs): 2162917Reference(s) to other database(s): GTC:G24838AS
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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