Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes)
Associated disease: infection due to Streptococcus pneumoniae [ICD11:
XN3PW 
]
The structure was elucidated in this paperNCBI PubMed ID: 2162257Publication DOI: 10.1016/0008-6215(90)84277-2Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, Sweden.
Application of methylation analysis, specific degradations, and n.m.r. spectroscopy to the capsular polysaccharide elaborated by Streptococcus pneumoniae type 7A indicates a hexasaccharide repeating-unit with the structure (Formula; see text).
Structure type: oligomer
Location inside paper: p.73, table V, p.74, structure 4
Compound class: CPS
Contained glycoepitopes: IEDB_130648,IEDB_136105,IEDB_137340,IEDB_137473,IEDB_141807,IEDB_142488,IEDB_146664,IEDB_151531,IEDB_225177,IEDB_885823,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, GLC-MS, partial acid hydrolysis, Smith degradation, de-O-acetylation, methylation (Hakomori method)
Comments, role: tetrasaccharide was obtained by acid hydrolysis of the O-deacetylated CPS
Related record ID(s): 2624, 2625, 2626, 2628, 115860
NCBI Taxonomy refs (TaxIDs): 1313Reference(s) to other database(s): GTC:G98391GJ, GlycomeDB:
16860
Show glycosyltransferases
NMR conditions: in D2O at 343(H) K
[as TSV]
13C NMR data:
missing...
1H NMR data:
Linkage Residue H1 H2 H3 H4 H5 H6
3 bDGlcp 4.50 3.37 3.42 3.30 3.40 3.61-3.89
2 Ac - 2.03-2.05
4,2,2 Ac - 2.03-2.05
4,2 aDGlcpN 4.98 3.93 3.82 3.53 3.93 3.81-3.93
4 aLRhap 5.20 4.20 3.96 3.58 3.78 1.33
bDGalpN 4.73 3.92 3.88 4.20 ? ?
1H NMR data:
| Linkage | Residue | H1 | H2 | H3 | H4 | H5 | H6 |
|---|
| 3 | bDGlcp | 4.50 | 3.37 | 3.42 | 3.30 | 3.40 | 3.61
3.89 |
| 2 | Ac |
| 2.03
2.05 | |
| 4,2,2 | Ac |
| 2.03
2.05 | |
| 4,2 | aDGlcpN | 4.98 | 3.93 | 3.82 | 3.53 | 3.93 | 3.81
3.93 |
| 4 | aLRhap | 5.20 | 4.20 | 3.96 | 3.58 | 3.78 | 1.33 |
| | bDGalpN | 4.73 | 3.92 | 3.88 | 4.20 | ? | ? |
|
There is only one chemically distinct structure:
Found 
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