Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 21861990Publication DOI: 10.1016/j.carres.2011.07.021Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: perepel
ioc.ac.ru
Institutions: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
A structure of the O-polysaccharide (O-antigen) of Escherichia coli O158 has been reported (Datta, A. K.; Basu, S.; Roy, N. Carbohydr. Res.1999, 322, 219-227). In this work, we reinvestigated the O158 polysaccharide using sugar analyses, Smith degradation, and (1)H and (13)C NMR spectroscopy and established the following structure, which is at variance with the structure established earlier: [see formula in text]. This structure is in agreement with the predicted functions of genes found in the O-antigen gene cluster of E. coli O158.
O-antigen, Escherichia coli, O-antigen gene cluster, O-Polysaccharide structure
Structure type: suggested polymer biological repeating unit
Location inside paper: abstract, p.2276, fig.2, 3
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_135813,IEDB_136105,IEDB_137340,IEDB_141807,IEDB_142488,IEDB_146664,IEDB_151531,IEDB_225177,IEDB_885813,IEDB_885823,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, sugar analysis, GLC, mild acid hydrolysis, Smith degradation
Comments, role: the structure OPS of E.coli O158 established in this work; revised structure from ID 1287
Related record ID(s): 1287, 20691, 26309, 26908
NCBI Taxonomy refs (TaxIDs): 2162918Reference(s) to other database(s): GTC:G84181EV
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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