Show legend Show as text

Structure type: monomer
C₂₁H₂₀O₁₂
Trivial name: myricitrin
Compound class: glycoside, flavonoid glycoside, flavonol glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 10944
  Ho LK, Lin WN "Quercetin 5,4'-dimethyl ether from Rhododendron ellipticum" - Phytochemistry 39 (1995) 463-464
  

  From the leaf of Rhodedrndron ellipticum β-carotene, sitosterol, uvaol, quercetin, myricetin, quercitrin, myricitrin, hyperin, quercetin 3-glucoside, and the new aglycone quercetin 5,4′-dimethyl ether were characterized by spectroscopic analysis and/or comparison with authentic samples.

  quercetin, Rhododendron ellipticum, qricaceae, myricetin, quercitrin, myricitrin, hyperin, quercetin 3-glucoside, quercetin 5, 4′-dimethyl ether

  Publication DOI: 10.1016/0031-9422(94)00905-9
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: Department of Pharmacology, National Yang-Ming University, Taipei, Taiwan, R.O.C., Institute of Chinese Medicine, China Medical College, Taichung, Taiwan, R.O.C.
  Methods: 13C NMR, 1H NMR, EI-MS, IR, TLC, CC
  
   
  
  Rhododendron ellipticum
  CSDB ID 146797 (all data & tools)
• Article ID: 11090
  Zhong XN, Otsuka H, Ide T, Hirata E, Takushi A, Takeda Y "Three flavonol glycosides from leaves of Myrsine seguinii" - Phytochemistry 46(5) (1997) 943-946
  

  From the leaves of Myrsine seguinii, five flavonol glycosides were isolated. Two were identified as quercitrin and myricitrin, and the structures of the remaining three are quercetin 3-rhamnoside-3'-glucoside,myricetin 3-rhamnoside-3'-glucoside, and myricetin 3,4'-dirhamnoside.

  flavonol glycosides, quercitrin, myricitrin, Myrsine seguinii, Rapanea neriifolia, Myrsinaceae

  Publication DOI: 10.1016/S0031-9422(97)00366-X
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, l-2-3 Kasumi, Minami-ku, Hiroshtma 734, Japan
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, extraction
  
   
  
  Myrsine seguinii
  CSDB ID 60063 (all data & tools)
• Article ID: 12080
  Lei H, Wei L, Lin W "Chemical constituents of Geranium dahuricum DC" - Yao xue xue bao = Acta pharmaceutica Sinica [Chinese] 35(1) (2000) 67-69
  

  Components were separated by means of solvent extraction and chromatography on Toyopeal and Sephadex LH20, the structures were determined by spectral analysis and chemical evidences. Five compounds were obtained and elucidated as methyl-3-O-(β-D-glucopyranosyl)-gallate (I), methyl-3-O-[β-D-(6′-O-galloyl)-glucopyranosyl]-gallate (II), quercetin 3-O-β-D-galactopyranoside (III), myricetin 3-O-β-D-galactopyranoside (IV), myricetin 3-O-α-L-rhamnopyranoside (V). These compounds were separated from this plant for the first time, where I and II were new natural products.

  quercetin, myricetin, Geranium dahuricum DC, methyl gallate

  Journal NLM ID: 21710340R
  Publisher: Beijing: Zhongguo yao xue hui
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, extraction, CC, melting point determination
  
   
  
  Geranium dahuricum
  CSDB ID 65122 (all data & tools)
• Article ID: 12246
  Hou AJ, Peng LY, Liu YZ, Lin ZW, Sun HD "Gallotannins and related polyphenols from Pistacia weinmannifolia" - Planta Medica 66(7) (2000) 624-626
  

  Two new gallotannins, pistafolins A (1) and B (2), were isolated from the leaf extract of Pistacia weinmannifolia. Their structures were determined by spectral methods. Four known gallotannins (3 - 6), seven known flavonoid glycosides (7 - 13), along with 1-O-β-D-(6′-O-galloyl)-glucopyranosyl-3-methoxy-5-hydroxybenzene (14), gallic acid (15), methyl gallate (16), (+)-catechin (17), and (+)-gallocatechin (18), were also isolated. Some of these compounds were tested for their cytotoxicity toward K562 cells, and two small molecular phenolic compounds, 15 and 18, showed significant inhibitory effects with IC50 values less than 5 μg/ml.

  cytotoxicity, B, polyphenols, Anacardiaceae, Pistacia weinmannifolia, gallotannin, pistafolins A

  NCBI PubMed ID: 11105566
  Publication DOI: 10.1055/s-2000-8633
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: hdsun@mail.kib.ac.cn
  Institutions: Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, China, Department of Phytochemistry, Henan College of Traditional Chinese Medicine, Zhengzhou, China
  Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, UV, extraction, optical rotation measurement, CC, cytotoxicity assay, evaporation, HR-FAB-MS
  
   
  
  Pistacia weinmannifolia
  CSDB ID 65853 (all data & tools)
• Article ID: 12261
  Kandil FE, Ahmed KM, Hussieny HA, Soliman AM "A new flavonoid from Limonium axillare" - Archiv Der Pharmazie [German] 333(8) (2000) 275-277
  

  A new flavonol glycoside identified as myricetin 3-O-β-D-sorboside (1) has been isolated from the leaves of L. axillare. The new compound showed a moderate inhibition of Ehrlich ascites carcinoma cells.

  antitumor activity, flavonoids, flavonol glycoside, Limonium axillare

  NCBI PubMed ID: 11008378
  Publication DOI: 10.1002/1521-4184(20008)333:8<275::aid-ardp275>3.0.co;2-4
  Journal NLM ID: 0330167
  Publisher: Deutschen Apotheker-Vereins
  Institutions: Natural and Microbial Products Department, National Research Centre, Cairo, Egypt, Chemistry of Tanning Materials and Proteins Department, National Research Centre, Cairo, Egypt, Pharmaceutical Department, National Research Centre, Cairo, Egypt, Medicinal Chemistry Department, National Research Centre, Cairo, Egypt
  Methods: 13C NMR, 1H NMR, acid hydrolysis, biological assays, paper chromatography, UV, extraction, CC, cytotoxicity assay, PPC
  
   
  
  Limonium axillare
  CSDB ID 65923 (all data & tools)
• Article ID: 12269
  Kawanishi K, Farnsworth NR "Current status of the chemistry and synthesis of natural antimalarial compounds and natural substances used to alleviate symptoms of diabetes (aldose reductase and α-glucosidase inhibitors)" - Book: Studies in Natural Products Chemistry (series: Bioactive Natural Products) (2000) Vol. 22, Chapter C, 145-192
  

  Atropine, camptothecin, cocaine, digitoxin, digoxin, morphine, pilocarpine, quinine, taxol, vinblastine and vincristine, among others, are important drugs obtained from higher plants and are used clinically. They have also served as lead compounds for the synthesis and modification of more effective and safer drugs, in many cases. In this chapter, drugs used as antimalarial compounds and for the complications of diabetes (aldose reductase and α-glucosidase inhibitors) will be discussed. Natural product chemists have isolated as little as 1.0 mg of pure compounds from natural sources and have been able to determine their structures using high resolution instrumental techniques. Organic chemists have synthesized thousands of compounds to produce one new drug on the basis of natural product leads, and pharmacologists and biochemists have tested their biological activity. Recently chemists and pharmacologists have worked together to develop techniques for studying structure-activity relationships using computer graphics and have designed new drugs. Biochemists, molecular biologists and pharmacologists have identified many receptors on which drugs act. Thus, mechanisms of drug action at the molecular level are being identified. From the accumulation of these results structure-activity relationships will lead to the preparation of thousands of useful compounds. We must produce drugs in these ways, because we cannot rely on solely on the limited amount of active compounds produced naturally in plants, in many cases, for a number of reasons. However we need to employ plant extracts themselves, because there are millions of people who cannot buy expensive synthetic drugs in the world and these extracts are widely used by them.

  Publication DOI: 10.1016/S1572-5995(00)80025-3
  Publisher: New York: Elsevier
  Editors: Atta-ur-Rahman
  Institutions: Kobe Pharmaceutical University, Kobe, Japan, Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA
  
   
  
  (plant)
  CSDB ID 65945 (all data & tools)
• Article ID: 12333
  Laitinen M-L, Julkunen-Tiitto R, Rousi M "Variation in phenolic compounds within a birch (Betula pendula) population" - Journal of Chemical Ecology 26(7) (2000) 1609-1622
  

  In previous studies, the qualitative and quantitative variation found in defense chemistry among birch populations and even among individual clones has been considerable. However, information about variation among adult, naturally regenerated birch trees from natural populations is still lacking. In this study, the phenolic composition of leaves of 30 naturally regenerated 20-year-old birch (Betula pendula) trees was analyzed for two successive years in order to characterize the chemical composition of individual trees, analyze the annual variation, and determine chemical similarities among individual trees within a population. The main phenolic compounds were flavonoid glycosides, myricetin, and quercetin derivatives. Annual variation in concentration among leaves was large. In most trees, concentrations were markedly higher in 1998 than in 1997; for certain compounds, the detected increase was as much as a 50%. However, for some individual trees, there were no differences between years in chemical quantity. Thus, when selection or grouping of trees is based on secondary chemistry, quantitative variation should be considered carefully. With the qualitative UPGMA method of classification, four chemotypes were found. The grouping was similar for both years, and qualitatively the results of an individual tree seem to be independent of sampling year. The stability in chemical profile of individual trees suggests that quality is tightly controlled by genotype, which provides a recognition tool for chemotaxonomy. The high within-population variation found in leaf defense chemistry may provide protection against different types of insects (generalists or specialists) and, thus, have positive effects on population survival.

  variation, population, chemotype, phenolic compounds, birch, Betulaceae, Betula pendula

  Publication DOI: 10.1023/A:1005582611863
  Journal NLM ID: 7505563
  Publisher: Springer
  Correspondence: mllaitin@cc.joensuu.fi
  Institutions: Finnish Forest Research Institute, Punkaharju Research Station, Punkaharju, Finland, Department of Biology, University of Joensuu, Joensuu, Finland
  
   
  
  Betula pendula
  CSDB ID 66182 (all data & tools)
• Article ID: 12334
  Lamba SS, Buch KY, Lewis III H, Lamba J "Phytochemicals as potential hypoglycemic agents" - Book: Studies in Natural Products Chemistry (series: Bioactive Natural Products) (2000) Vol. 21, Chapter B, 457-496
  

  Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration (hyperglycemia) which is due to insulin deficiency and/or insulin resistance. Hyperglycemia occurs because the liver and skeletal muscle cannot store glycogen and the tissues are unable to take up and utilize glucose. Treatment of diabetes is afforded by the following: (i) diet and exercise, (ii) insulin replacement therapy and (iii) the use of oral hypoglycemic agents. In folklore, a variety of plant extracts have been used to treat diabetic patients for centuries. Folklore has given the field of medicine many useful drugs, such pharmacologic prototypes include Digitalis(digitoxin, digoxin), Atropa, Hyoscyamnsand Datura(atropine, scopolamine), Catharanthus(vincristine, vinblastine), Erythroxylon(cocaine), Claviceps(ergonovine, ergotamine), Papaver(morphine, codeine and papaverine), Pilocarpus(pilocarpine) Rauvolfia(reserpine, rescinnamine, deserpidine), and Cinchona(quinine, quinidine); and many others. Obviously evaluation of plants and their active constituents has proven a very useful way of obtaining several useful therapeutic agents. Hence, a logical review of plant constituents having hypoglycemic activity could provide useful clues for obtaining new hypoglycemic agents. Plant constituents reportedly possessing hypoglycemic activity can be classified as follows: 1. Alkaloids; 2. Flavonoids and related compounds; 3. Glycosides/Steroids/Terpenoids; 4. Polysaccharides/ Proteins; and 5. Miscellaneous compounds. Phytoconstituents based upon the above classification are discussed including selected names of plants which are listed alphabetically according to genus. Appropriate data on their pharmacological activity, mechanisms of action (where applicable), and other relevant properties are discussed.

  diabetes mellitus, hypoglycemic activity, natural drugs

  Publication DOI: 10.1016/S1572-5995(00)80012-5
  Publisher: New York: Elsevier
  Editors: Atta-ur-Rahman
  Institutions: Florida A & M University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, USA, Parke-Davis, Division of Warner-Lambert Company, Morris Plain, USA
  
   
  
  (plant)
  CSDB ID 66191 (all data & tools)
• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66242 (all data & tools)
• Article ID: 12379
  Ivancheva S, Petrova A "A chemosystematic study of eleven Geranium species" - Biochemical Systematics and Ecology 28(3) (2000) 255-260
  

  The flavonoids of 11 species from six sections (Geranium, Batrachioides, Lucida, Unguiculata, Robertium, Erodioideae) of the genus Geranium have been studied. Quercetin and its derivatives were the most common aglycones with lesser amounts of kaempferol, myricetin and luteolin. Glycosylation was found mainly in the 3 or 4′ positions and to a lesser extent in the 7 position. Chemosystematic relationships are discussed. The occurrence of exudate flavonoids various methyl ether of kaempferol, quercetin and myricetin has been detected in all the 11 species surveyed.

  flavonoid glycosides, chemosystematics, Geranium, flavonoid aglycones

  Publication DOI: 10.1016/S0305-1978(99)00060-5
  Journal NLM ID: 0430442
  Publisher: Pergamon Press
  Correspondence: Ivancheva S
  Institutions: Institute of Botany, Bulgarian Academy of Sciences, Sofia, Bulgaria
  Methods: TLC, extraction, CC, evaporation
  
   
  
  Geranium sylvaticum, Geranium lucidum, Geranium macrorrhizum
  CSDB ID 66418 (all data & tools)
• Article ID: 12401
  Lin L-C, Kuo Y-C, Chou C-J "Anti-herpes simplex virus type-1 flavonoids and a new flavanone from the root of Limonium sinense" - Planta Medica 66(4) (2000) 333-336
  

  From the root of Limonium sinense (Girard) Ktze a new (2R,3S)-3,5,7,4′-tetrahydroxy-3′,5′-dimethoxyflavanone was isolated and named isodihydrosyringetin (3), together with nine other known compounds, (-)-epigallocatechin 3-O-gallate (1), samarangenin B (2), myricetin (4), myricetin 3-O-α-rhamnopyranoside (5), quercetin 3-O-α-rhamnopyranoside (6), (-)-epigallocatechin (7), gallic acid (8), N-trans-caffeoyltyramine (9), and N-trans-feruloyltyramine (10). All of them were examined for their inhibitory effects on herpes simplex virus type-1 (HSV-1) replication in Vero cells. Both compounds 1 and 2 exhibited potent inhibitory activities in HSV-1 replication. Comparison of the IC50 values indicated that compounds 1 and 2 had higher inhibitory activities than the positive control acyclovir (38.6 ± 2.6 vs. 55.4 ± 5.3 μM, P < 0.001; 11.4 ± 0.9 vs. 55.4 ± 5.3 μM, P < 0.0005). Cytotoxicity was unlikely involved because no cell deaths were observable in the Vero cells following 5 day treatments with compound 1 or 2.

  inhibition, Limonium sinense, Plumbaginaceae, isodihydrosyringetin, herpes simplex virus type-1

  NCBI PubMed ID: 10865449
  Publication DOI: 10.1055/s-2000-8540
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: lclin@cma23.nricm.edu.tw
  Institutions: National Research Institute of Chinese Medicine, Taipei, Taiwan, China
  Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, biological assays, HPLC, alkaline hydrolysis, extraction, CI-MS, HR-ESI-MS, cytotoxicity assay, evaporation, centrifugation
  
   
  
  Limonium sinense
  CSDB ID 66505 (all data & tools)
• Article ID: 12402
  Lin L-C, Chou C-J "Flavonoids and phenolics from Limonium sinense" - Planta Medica 66(4) (2000) 382-383
  

  From the aerial part of Limonium sinense (Girard) Ktze, a new flavonol glycoside, myricetin 3-O-(2″-O-p-hydroxybenzoyl)-α-rhamnopyranoside has been isolated together with known flavonols, flavonol glycosides, flavonol glycoside gallates, flavones, flavanones, flavan-3-ols and gallic acid. The structural determinations of these compounds were based on spectral analyses.

  structural determination, phenolics, flavonoid glycosides, Limonium sinense

  NCBI PubMed ID: 10865464
  Publication DOI: 10.1055/s-2000-8547
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: lclin@cma23.nricm.edu.tw
  Institutions: National Research Institute of Chinese Medicine, Taipei, Taiwan, China
  Methods: 13C NMR, 1H NMR, EI-MS, NMR-2D, TLC, HPLC, extraction, evaporation, centrifugation, HR-EI-MS
  
   
  
  Limonium sinense
  CSDB ID 66508 (all data & tools)
• Article ID: 12487
  Min BS, Nakamura N, Miyashiro H, Kim Y-H, Hattori M "Inhibition of human immunodeficiency virus type 1 reverse transcriptase and ribonuclease H activities by constituents of Juglans mandshurica" - Chemical and Pharmaceutical Bulletin 48(2) (2000) 194-200
  

  From the stem-bark of Juglans mandshurica, two new naphthalenyl glucopyranosides, 1, 4, 8-trihydroxy-nahthalene 1-O-[α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside] (1) and 1, 4, 8-trihydroxynaphthalene 1-O-β-D[6'-O-(3", 5"-dihydroxy-4"-methoxybenzoyl)]glucopyranoside (4), and two new α-tetralonyl glucopyranosides, 4α, 5, 8-trihydroxy-α-tetralone 5-O-β-D-[6'-O-(3", 5"-dihydroxy-4"-methoxybenzoyl)glucopyranoside (7) and 4α, 5, 8-trihydroxy-α-tetralone 5-O-β-D-[6'-O-(3", 4", 5"-trihydroxybenzoyl)glucopyranoside (8), were isolated together with three known naphthalenyl glucopyranosides (2, 3 and 5), one α-tetralonyl glucopyranoside (6), four flavonoids (9-12), and two gaalloyl glucopyranosides (13, 14).Amongst the isolated compounds, 1, 2, 6-trigalloylglucopyranose (13) and 1, 2, 3, 6-tertagalloylglucopyranose (14) exhibited the most potent inhibition of reverse transcriptase (RT) activity with IC50 values of 0.067 and 0.040 μM, respectively, while the latter compound also inhibited ribonuclease H (RNase H) activity with an IC50 of 39 μM, comparable in potency to illimaquinone used as a positive contorl. 1, 4, 8-Trihydroxy-naphthalene 1-O-β-D-glucopyranoside (2), 1, 4, 8-trihydroxynaphthalene 1-O-β-D-[6'-O-(4"-hydroxy-3", 5"-dimethoxybenzoyl)]glu-copyranoside (3) and 8 showed moderate inhibition against both enyzme activities, and inhibitory potency of 2 against RNase H activity (IC50=156 μM) was slightly greater than that against the RT activity (IC50=290 μM).The inhibitory potencies of 4α, 5, 8-trihydroxy-α-tetralone 5-O-β-D-[6'-O-4"-hydroxy-3", 5"-dimethoxybenzoyl)] glucopyranoside (6), 7 and 8 against RT activity increased accompanied by an increase in the number of free hydroxyls on the galloyl residues, as represented by the IC50 values of >500, 330 and 5.8 μM, respectively.

  reverse transcriptase, Juglans mandshurica, human immunodeficienc virus, naphthalenyl glucopyranoside, ribonuclease H, α-tetralonyl glucopyranoside

  NCBI PubMed ID: 10705503
  Publication DOI: 10.1248/cpb.48.194
  Journal NLM ID: 0377775
  Publisher: Pharmaceutical Society Of Japan
  Institutions: College of Pharmacy, Chungnam National University, Taejeon, South Korea, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
  Methods: biological assays
  
   
  
  Juglans mandshurica
  CSDB ID 66895 (all data & tools)
• Article ID: 12642
  Salatino A, Salatino MLF, Giannasi DE "Flavonoids and the taxonomy of Cercis" - Biochemical Systematics and Ecology 28(6) (2000) 545-550
  

  Flavonoids of 11 samples of Cercis, comprising seven species, were isolated and identified. Only 3-O-monoglycosides of kaempferol, quercetin and myricetin were obtained. Bauhinia (the largest genus in tribe Cercideae) is akin to Cercis because flavones are rarely found in the former. On the other hand, species of Bauhinia often present glycosides of isorhamnetin and a wider diversity of glycosides, and only rarely present myricetin. The frequent occurrence of this flavonol and the simpler flavonoid profile of Cercis may reflect a greater antiquity of Cercis as compared with Bauhinia. With the exception of C. canadensis var. mexicana, Cercis taxa from xerophytic habitats did not yield kaempferol glycosides in detectable amounts, as opposed to taxa from mesophytic habitats. The results obtained are consistent with proposals of merging C. reniformis into synonymy of C. occidentalis, as well as the recognition of two North American species, C. canadensis and C. occidentalis, and the recognition of the Asian C. gigantea.

  Cercis; Cercideae; flavonoids; myricetin; chemotaxonomy

  NCBI PubMed ID: 10793254
  Publication DOI: 10.1016/s0305-1978(99)00093-9
  Journal NLM ID: 0430442
  Publisher: Pergamon Press
  Correspondence: Salatino A
  Institutions: Department of Botany, University of Georgia, Athens, USA, Institute of Biosciences, University of São Paulo, São Paulo, Brazil
  Methods: paper chromatography, extraction, CC, evaporation
  
   
  
  Cercis canadensis, Cercis canadensis ssp. mexicana, Cercis chinensis, Cercis chingii, Cercis gigantea, Cercis occidentalis, Cercis reniformis, Cercis siliquastrum
  CSDB ID 67637 (all data & tools)
• Article ID: 12739
  Tahrouch S, Andary C, Rapior S, Mondolot L, Gargadennec A, Fruchier A "Polyphenol investigation of Argania spinosa (Sapotaceae) endemic tree from Morocco" - Acta Botanica Gallica : Bulletin De La Société Botanique De France 147(3) (2000) 225-232
  

  The leaves of Argania spinosa from Morocco were investigated for flavonoids and condensed tannins. Four flavonol glycosides were identified by 1H NMR as myricitrin, quercitrin, hyperoside and myricetin 3-O-galactoside. UV spectrophotometric and histochemical methods were carried out to quantify and locate flavonoids and condensed tannins from leaves, stems and thorns of A. spinosa. Both high content and cell localisation of total polyphenols could explain the Argan tree adaptation to aridity.

  flavonol glycosides, Sapotaceae, condensed tannins, Argania spinosa, histochemistry

  Publication DOI: 10.1080/12538078.2000.10515843
  Journal NLM ID: 100955707
  Publisher: La Société
  Institutions: Laboratoire des Symbiotes Racinaires et de Biochimie Végétale, Département de Biologie, Faculté des Sciences, Université Ibnou Zohr, Agadir, Maroc, Laboratoire de Botanique, Phytochimie et Mycologie, UMI—CNRS (UPR 9056, CEFE), Faculté de Pharmacie, Université Montpellier I, Montpellier, France, Laboratoire de Chimie Organique, Ecole Nationale Supérieure de Chimie, Montpellier, France
  Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, TLC, ESI-MS, HPLC, extraction, CC
  
   
  
  Argania spinosa
  CSDB ID 68086 (all data & tools)

Show legend Show as text

Structure type: monomer
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12246
  Hou AJ, Peng LY, Liu YZ, Lin ZW, Sun HD "Gallotannins and related polyphenols from Pistacia weinmannifolia" - Planta Medica 66(7) (2000) 624-626
  

  Two new gallotannins, pistafolins A (1) and B (2), were isolated from the leaf extract of Pistacia weinmannifolia. Their structures were determined by spectral methods. Four known gallotannins (3 - 6), seven known flavonoid glycosides (7 - 13), along with 1-O-β-D-(6′-O-galloyl)-glucopyranosyl-3-methoxy-5-hydroxybenzene (14), gallic acid (15), methyl gallate (16), (+)-catechin (17), and (+)-gallocatechin (18), were also isolated. Some of these compounds were tested for their cytotoxicity toward K562 cells, and two small molecular phenolic compounds, 15 and 18, showed significant inhibitory effects with IC50 values less than 5 μg/ml.

  cytotoxicity, B, polyphenols, Anacardiaceae, Pistacia weinmannifolia, gallotannin, pistafolins A

  NCBI PubMed ID: 11105566
  Publication DOI: 10.1055/s-2000-8633
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: hdsun@mail.kib.ac.cn
  Institutions: Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, China, Department of Phytochemistry, Henan College of Traditional Chinese Medicine, Zhengzhou, China
  Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, UV, extraction, optical rotation measurement, CC, cytotoxicity assay, evaporation, HR-FAB-MS
  
   
  
  Pistacia weinmannifolia
  CSDB ID 65855 (all data & tools)
• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66245 (all data & tools)
• Article ID: 12402
  Lin L-C, Chou C-J "Flavonoids and phenolics from Limonium sinense" - Planta Medica 66(4) (2000) 382-383
  

  From the aerial part of Limonium sinense (Girard) Ktze, a new flavonol glycoside, myricetin 3-O-(2″-O-p-hydroxybenzoyl)-α-rhamnopyranoside has been isolated together with known flavonols, flavonol glycosides, flavonol glycoside gallates, flavones, flavanones, flavan-3-ols and gallic acid. The structural determinations of these compounds were based on spectral analyses.

  structural determination, phenolics, flavonoid glycosides, Limonium sinense

  NCBI PubMed ID: 10865464
  Publication DOI: 10.1055/s-2000-8547
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: lclin@cma23.nricm.edu.tw
  Institutions: National Research Institute of Chinese Medicine, Taipei, Taiwan, China
  Methods: 13C NMR, 1H NMR, EI-MS, NMR-2D, TLC, HPLC, extraction, evaporation, centrifugation, HR-EI-MS
  
   
  
  Limonium sinense
  CSDB ID 66510 (all data & tools)

Show legend Show as text

Structure type: monomer ; 631 [M+H]+
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66239 (all data & tools)

Show legend Show as text

Structure type: monomer ; 631 [M+H]+
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66240 (all data & tools)

Show legend Show as text

Structure type: monomer ; 769 [M+H]+
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66241 (all data & tools)

Show legend Show as text

Structure type: monomer
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66243 (all data & tools)

Show legend Show as text

Structure type: monomer
Compound class: glycoside, flavonoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

• Article ID: 12346
  Lee TH, Qiu F, Waller GR, Chou CH "Three new flavonol galloylglycosides from leaves of Acacia confusa" - Journal of Natural Products 63(5) (2000) 710-712
  

  Myricetin 3-O-(2‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (1), myricetin 3-O-(3‘‘-O-galloyl)-α-rhamnopyranoside 7-methyl ether (2), and myricetin 3-O-(2‘‘,3‘‘-di-O-galloyl)-α-rhamnopyranoside (3), three new flavonol galloylglycosides, were isolated from leaves of Acacia confusa sampled from Chaoushi in the north of Taiwan. Their structures were established by analysis of spectroscopic data, and the compounds were evaluated for anti-hatch activity against brine shrimp.

  flavonol glycosides, brine shrimp, Acacia confusa, anti-hatch activity

  NCBI PubMed ID: 10843598
  Publication DOI: 10.1021/np990482w
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: chou@gate.sinica.edu.tw
  Institutions: Institute of Botany, Academia Sinica, Taipei, Taiwan, China, Department of Chemistry, Oklahoma State University, Stillwater, USA, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, USA, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, China
  
   
  
  Acacia confusa
  CSDB ID 66244 (all data & tools)
• Article ID: 12402
  Lin L-C, Chou C-J "Flavonoids and phenolics from Limonium sinense" - Planta Medica 66(4) (2000) 382-383
  

  From the aerial part of Limonium sinense (Girard) Ktze, a new flavonol glycoside, myricetin 3-O-(2″-O-p-hydroxybenzoyl)-α-rhamnopyranoside has been isolated together with known flavonols, flavonol glycosides, flavonol glycoside gallates, flavones, flavanones, flavan-3-ols and gallic acid. The structural determinations of these compounds were based on spectral analyses.

  structural determination, phenolics, flavonoid glycosides, Limonium sinense

  NCBI PubMed ID: 10865464
  Publication DOI: 10.1055/s-2000-8547
  Journal NLM ID: 0066751
  Publisher: George Thieme
  Correspondence: lclin@cma23.nricm.edu.tw
  Institutions: National Research Institute of Chinese Medicine, Taipei, Taiwan, China
  Methods: 13C NMR, 1H NMR, EI-MS, NMR-2D, TLC, HPLC, extraction, evaporation, centrifugation, HR-EI-MS
  
   
  
  Limonium sinense
  CSDB ID 66509 (all data & tools)