Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: diarrhea [ICD11:
ME05.1 
, ICD11:
SA55 ];
hemorrhagic colitis (HC) [ICD11:
1A40.0 ];
hemolytic-uremic syndrome (HUS) [ICD11:
3A21.2 ];
infection due to Escherichia coli [ICD11:
XN6P4 ]
The structure was elucidated in this paperNCBI PubMed ID: 22562778Publication DOI: 10.1007/s10719-012-9383-4Journal NLM ID: 8603310Publisher: Kluwer Academic Publishers
Correspondence: akmisra69
gmail.com
Institutions: Division of Molecular Medicine, Bose Institute, P-1/12, C.I.T. Scheme VII M, Kolkata, 700054, India
An acidic pentasaccharide repeating unit corresponding to the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113 as its p-methoxyphenyl glycoside has been synthesized in a convergent manner by adopting a [3+2] block glycosylation strategy. During the synthetic endeavor a one-pot reaction condition for stereoselective glycosylation and protecting group manipulation has been applied. All glycosylation steps are highly stereoselective with good to excellent yield.
O-antigen, pentasaccharide, glycosylation, enterohaemorrhagic, Escherichia coli O113
Structure type: oligomer
Location inside paper: p.182, fig.2, 1
Aglycon: p-methoxyphenyl
Trivial name: repeating unit
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_130648,IEDB_134627,IEDB_135813,IEDB_136044,IEDB_136906,IEDB_137340,IEDB_137472,IEDB_137473,IEDB_1391961,IEDB_1391963,IEDB_141584,IEDB_141794,IEDB_141807,IEDB_143260,IEDB_151528,IEDB_151531,IEDB_190606,IEDB_885822,SB_165,SB_166,SB_187,SB_195,SB_23,SB_24,SB_7,SB_8,SB_88
Methods: 13C NMR, 1H NMR, TLC, ESI-MS, chemical methods, glycosylation
Synthetic data: chemical
Related record ID(s): 27302
NCBI Taxonomy refs (TaxIDs): 1162729Reference(s) to other database(s): GTC:G39690XV
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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