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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Host organism: Sus scrofa domestica
Organ / tissue: lung, heart
Associated disease: pig pneumonia; pericarditis

The structure was elucidated in this paper
NCBI PubMed ID: 22704198
Publication DOI: 10.1016/j.carres.2012.05.010
Journal NLM ID: 0043535
Publisher: Elsevier
Correspondence: A. Silipo <silipo

unina.it>
Institutions: Dipartimento di Scienze Chimiche, Universita di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy, Istituto di Chimica e Tecnologia dei Polimeri—ICTP, CNR, Via P. Gaifami 18, 95126 Catania, Italy

Uruburuella suis is a novel species isolated from lungs and heart of pigs with pneumonia and pericarditis. Phenotypic and phylogenetic evidences showed that it represented a hitherto unknown subline within the family Neisseriaceae. In the present work we defined the whole structure of the LPS isolated from Uruburuella suis. The structural determination, which was achieved by chemical, spectroscopic and spectrometric approaches, indicates a novel rough type lipopolysaccharide rich in negatively charged groups in the lipid A-inner core region. The elucidation of the structural features of the LPS from Uruburuella suis is a first step toward the comprehension of the characteristics of the cell envelope in such new and interesting microorganisms.

Lipopolysaccharide, NMR spectroscopy, Neisseriaceae, MS spectrometry, Uruburuella suis

Structure type: oligomer
Location inside paper: p.81
Compound class: LOS
Contained glycoepitopes: IEDB_120354,IEDB_123890,IEDB_130650,IEDB_130659,IEDB_130670,IEDB_135394,IEDB_135515,IEDB_135813,IEDB_136105,IEDB_137340,IEDB_140087,IEDB_140088,IEDB_140090,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_150908,IEDB_151531,IEDB_2189047,IEDB_225177,IEDB_226811,IEDB_534864,IEDB_885823,IEDB_983931,SB_192

Methods: 13C NMR, 1H NMR, GLC-MS, NMR-2D, 31P NMR, deacylation, acid hydrolysis, GLC, MALDI-TOF MS, composition analysis, NMR-1D
Comments, role: Positions of pyrophosphate and phosphoethanolamine groups are tentative.

Related record ID(s): 27318
NCBI Taxonomy refs (TaxIDs): 252130
Show glycosyltransferases

There is only one chemically distinct structure:

CCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@H]1[C@@H](OP(=O)(O)O)O[C@H](CO[C@@H]2O[C@H](CO[C@]3(C(=O)O)C[C@@H](O[C@]4(C(=O)O)C[C@@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O4)[C@@H](O[C@H]4O[C@H]([C@H](CO)OP(=O)(O)OCCN)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O[C@H]5O[C@H]([C@@H](O)CO[C@H]6O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H](O)[C@H](O[C@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8NC(C)=O)[C@H]7O[C@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@@H]5O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H]4O)[C@@H]([C@H](O)CO)O3)[C@@H](OP(=O)(O)OP(=O)(O)O)[C@H](OC(=O)C[C@H](O)CCCCCCCCC)[C@H]2NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](O)[C@@H]1OC(=O)C[C@H](O)CCCCCCCCC

SVG MW SMILES 3D mol Ionize