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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Citrobacter freundii [ICD11: XN0M3

]

The structure was elucidated in this paper
NCBI PubMed ID: 8821392
Publication DOI: 10.1111/j.1574-695X.1996.tb00209.x
Journal NLM ID: 9315554
Publisher: Elsevier
Correspondence: knirel

ioc.ac.ru
Institutions: N.D.Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

Structural analysis using 13C NMR spectroscopy and methylation showed that lipopolysaccharides (LPSs) of Citrobacter freundii O35 and Salmonella arizonae O59 have structurally identical O-specific polysaccharide chains, and those of C. freundii O38 and Salmonella kentucky differ only in the presence of O-acetyl groups in the former. Serological relationships between the structurally similar LPSs were demonstrated using inhibition of ELISA, rocket immunoelectrophoresis, double gel diffusion, and immunoblotting. The O-acetyl groups present in C. freundii O38 LPS are of little importance for its serological specificity. A cross-reaction was observed in immunoblotting between O-antisera to C. freundii O35 and S. arizonae O59 and a structurally related LPS of Pseudomonas aeruginosa O11a, 11b (Lanyi-Bergan classification).

Lipopolysaccharide, structure, Pseudomonas aeruginosa, O-specific polysaccharide, Salmonella, Citrobacter, immunospecificity, O-acetyl group

Structure type: polymer chemical repeating unit
Location inside paper: structure 3
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_130701,IEDB_136044,IEDB_136104,IEDB_137472,IEDB_141794,IEDB_142488,IEDB_143632,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_153217,IEDB_190606,IEDB_225177,IEDB_885823,IEDB_983930,IEDB_983931,SB_136,SB_165,SB_166,SB_187,SB_192,SB_195,SB_196,SB_44,SB_67,SB_7,SB_72,SB_88

Methods: 13C NMR, methylation
Biological activity: serological cross-reactivity
Comments, role: published polymerization frame was shifted for conformity with other records.

Related record ID(s): 2830, 2923, 2925
NCBI Taxonomy refs (TaxIDs): 546
Reference(s) to other database(s): GTC:G24986QG, GlycomeDB:37357
Show glycosyltransferases

There is only one chemically distinct structure:

*O[C@H]1[C@H](C)O[C@H](O[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2O[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2O[C@@H]2[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](*)O[C@H](CO)[C@@H]2O)[C@H](O)[C@@H]1O[C@H]1O[C@H](C)[C@H](OC(C)=O)C[C@H]1O

SVG MW SMILES 3D mol Ionize