Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: bacillary dysentery [ICD11:
1A02 
, ICD11:
XN7HG ];
urinary tract infections (UTI) [ICD11:
GC08 ];
infection due to Shigella boydii [ICD11:
XN8RN ];
infection due to Escherichia coli [ICD11:
XN6P4 ]
Publication DOI: 10.2174/1570179411310010010Journal NLM ID: 101208457Publisher: Saif Zone, Sharjah, UAE; San Francisco, CA: Bentham Science Publishers
Correspondence: akmisra69
gmail.com
Institutions: Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India
concise chemical synthesis of the common tetrasaccharide corresponding to the O-antigen of enteroinvasive Escherichia coli O143 and Shigella boydii type 8 has been achieved in excellent yield. Application of [2+2] block glycosylation and late stage oxidation of primary hydroxyl groups to the carboxylic groups are notable features in the synthetic strategy.
tetrasaccharide, O-antigen, Escherichia coli, Dysentery, Shigella boydii
Structure type: polymer chemical repeating unit
Location inside paper: p.178, fig.1
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130648,IEDB_135813,IEDB_137340,IEDB_137473,IEDB_1391961,IEDB_140630,IEDB_141584,IEDB_141807,IEDB_151527,IEDB_151531,IEDB_423153,IEDB_885822
Methods: 13C NMR, 1H NMR, chemical synthesis, chemical methods, glycosylation
Synthetic data: chemical
Related record ID(s): 29759
NCBI Taxonomy refs (TaxIDs): 621,
562Reference(s) to other database(s): GTC:G01795RA
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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