Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 23897032Publication DOI: 10.1007/s10858-013-9763-5Journal NLM ID: 9110829Publisher: ESCOM Science Publishers
Correspondence: G. Widmalm <gw
organ.su.se>
Institutions: Arrhenius Laboratory, Department of Materials and Environmental Chemistry, Stockholm University, Stockholm, Sweden
Carbon-13 relaxation data are reported for exocyclic groups of hexopyranosyl sugar residues in the repeating unit within the Escherichia coli O91 O-antigen polysaccharide in a dilute D2O solution. The measurements of T 1, T 2 and heteronuclear nuclear Overhauser enhancements were carried out at 310 K at two magnetic fields (16.4 T, 21.1 T). The data were analyzed using the standard and extended Lipari-Szabo models, as well as a conformational jump model. The extended version of the Lipari-Szabo and the two-site jump models were most successful for the hydroxymethyl groups of Gal and GlcNAc sugar residues. Different dynamics was found for the hydroxymethyl groups associated with different configurations (D-gluco, D-galacto) of the sugar residues, the latter being faster than the former.
carbohydrates, NMR spectroscopy, model free approach, biopolymer, two-site jump model
Structure type: suggested polymer biological repeating unit ; n=10
Location inside paper: p.38, fig.1
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130646,IEDB_135813,IEDB_136044,IEDB_137340,IEDB_137472,IEDB_140108,IEDB_140122,IEDB_140630,IEDB_141794,IEDB_141807,IEDB_151527,IEDB_151531,IEDB_190606,IEDB_423153,SB_165,SB_166,SB_187,SB_195,SB_30,SB_7,SB_88
Methods: NMR, conformation analysis
Comments, role: biological repeat frame was based on [PMID:15132695]
Related record ID(s): 895, 9226, 20701, 30235
NCBI Taxonomy refs (TaxIDs): 1055539
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There is only one chemically distinct structure:
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