Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria) Host organism: Homo sapiens
Associated disease: acute otitis media [ICD11:
AB00 , Life stage: adult];
chronic respiratory tract infections [ICD11:
CA45 , ICD11:
CB7Z ];
infection due to Haemophilus influenzae [ICD11:
XN1P6 ]
The structure was elucidated in this paper NCBI PubMed ID: 23582099 Publication DOI: 10.1016/j.carres.2013.03.011 Journal NLM ID: 0043535 Publisher: Elsevier
Correspondence: E.K.H. Schweda <elksc
ifm.liu.se>
Institutions: Clinical Research Centre, Karolinska Institutet, Novum, S-141 86 Huddinge, Sweden
We report the novel branching pattern in lipopolysaccharide (LPS) expressed by non-typeable Haemophilus influenzae (NTHi) strain 1232. The strain expressed the β-D-Glcp-(1→4)-[α-D-Galp-(1→4)-β-D-Galp-(1→7)]-D-α-D-Hepp-(1→6)-β-D-Glcp chain linked to the proximal heptose (HepI) of the conserved triheptosyl inner-core moiety of NTHi LPS: L-α-D-HepIIIp-(1→2)-[PEtn→6]-L-α-D-HepIIp-(1→3)-L-α-D-HepIp-(1→5)-[PPEtn→4]-α-Kdop-(2→6)-lipid A. The structure has been elucidated using NMR spectroscopy, electrospray ionization mass spectrometry (ESI-MS) and capillary electrophoresis coupled to electrospray ionization tandem mass spectrometry (CE-ESI-MS(n)) on O-deacylated LPS and core oligosaccharide (OS) materials, as well as HPLC-ESI-MS(n) on permethylated, dephosphorylated OS. It was also found that a tetrasaccharide unit bearing sialic acid [α-Neu5Ac-(2→3)-β-D-Galp-(1→4)-β-D-GlcNAcp-(1→3)-β-D-Galp-(1→] could substitute O-4 of the β-D-Glcp linked to HepI. In addition, the distal heptose (HepIII) was substituted by PCho→6-β-D-Galp-(1→ at the O-2 position.
Lipopolysaccharide, Haemophilus influenzae, NMR spectroscopy, D-glycero-D-manno-heptose, losA1, Sialyllacto-N-neotetraose
Structure type: oligomer
Location inside paper: p.121, fig.5
Aglycon: lipid A
Compound class: LPS
Contained glycoepitopes: IEDB_115009,IEDB_116046,IEDB_120354,IEDB_123890,IEDB_130646,IEDB_130650,IEDB_130651,IEDB_130697,IEDB_135813,IEDB_136044,IEDB_136794,IEDB_136906,IEDB_137340,IEDB_137472,IEDB_137776,IEDB_137777,IEDB_137779,IEDB_138949,IEDB_1391966,IEDB_139428,IEDB_140087,IEDB_140088,IEDB_140090,IEDB_140108,IEDB_140110,IEDB_140122,IEDB_140624,IEDB_141794,IEDB_141807,IEDB_142351,IEDB_142487,IEDB_142488,IEDB_144987,IEDB_146100,IEDB_146664,IEDB_148488,IEDB_149144,IEDB_149174,IEDB_150933,IEDB_151528,IEDB_151531,IEDB_190606,IEDB_2189046,IEDB_2189047,IEDB_423120,IEDB_742247,IEDB_983931,SB_115,SB_116,SB_131,SB_145,SB_165,SB_166,SB_170,SB_171,SB_172,SB_173,SB_187,SB_192,SB_195,SB_30,SB_31,SB_36,SB_39,SB_6,SB_62,SB_68,SB_7,SB_84,SB_88,SB_9
Methods: 13C NMR, 1H NMR, methylation, NMR-2D, GC-MS, HF solvolysis, de-O-acylation, sugar analysis, ESI-MS, mild acid hydrolysis, HPLC, CE-ESI-MS
Related record ID(s): 29797
NCBI Taxonomy refs (TaxIDs): 727
Show glycosyltransferases
There are 36 chemically distinct structures. Please, select:
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-3)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-4)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-6)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-2)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-3)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-2),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-3),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
xXCho?(1-P-6)[Ac(1-4)]bDGalp(1-2)[Ac(1-7)]aXLDmanHepp(1-2)[xXEt?N(1-P-6)]aXLDmanHepp(1-3)[Ac(1-5)aXNeup(2-3)bDGalp(1-4)[Ac(1-2)]bDGlcpN(1-3)bDGalp(1-4)[bDGlcp(1-4)[Ac(1-6),aDGalp(1-4)bDGalp(1-7)]aXDDmanHepp(1-6)]bDGlcp(1-4)]aXLDmanHepp(1-5)[xXEt?N(1-P-P-4)]aXKdop
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, Life stage: adult]; chronic respiratory tract infections [ICD11: CA45 
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