Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: diarrhea [ICD11:
ME05.1 
, ICD11:
SA55 ];
infection due to Salmonella enterica [ICD11:
XN5VC ];
infection due to Escherichia coli [ICD11:
XN6P4 ]
Publication DOI: 10.1016/j.tetasy.2013.04.001Journal NLM ID: 9010953Publisher: Oxford: Elsevier
Correspondence: A.K. Misra <akmisra69
gmail.com>
Institutions: Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII-M, Kolkata 700054, India
A concise chemical synthetic strategy has been developed for the synthesis of a pentasaccharide present in the O-antigen of Salmonella enterica O57 and Escherichia coli O51 strains. A sequential glycosylation strategy has been adopted for the synthesis of the target pentasaccharide. All intermediate steps are high yielding and the glycosylation steps are stereoselective. A number of recently developed methodologies have been used in the synthesis.
synthesis, O-antigen, repeating unit, Escherichia coli, Salmonella enterica, pentasaccharide
Structure type: oligomer
Location inside paper: p.607, fig.2, p.608, scheme 2, 1
Aglycon: 2-(p-methoxyphenoxy) ethyl
Compound class: O-antigen
Contained glycoepitopes: IEDB_130648,IEDB_133754,IEDB_135813,IEDB_136105,IEDB_137340,IEDB_137473,IEDB_141807,IEDB_142488,IEDB_143253,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_225177,IEDB_885823,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, MALDI-MS, chemical synthesis, chemical methods, glycosylation
Synthetic data: chemical
Related record ID(s): 29181
NCBI Taxonomy refs (TaxIDs): 28901,
2079160Reference(s) to other database(s): GTC:G84780JA
Show glycosyltransferases
There is only one chemically distinct structure:
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