Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperPublication DOI: 10.1016/j.tetasy.2014.03.007Journal NLM ID: 9010953Publisher: Oxford: Elsevier
Correspondence: akmisra69
gmail.com (A.K. Misra)
Institutions: Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII-M, Kolkata 700054, India
A straightforward linear synthetic strategy has been developed for the synthesis of the pentasaccharide repeating unit of the cell wall O-antigenic polysaccharide of enteroadherent Escherichia coli O154 strain. Newly developed glycosylation conditions using glycosyl trichloroacetimidate derivatives as glycosyl donors and nitrosyl tetrafluoroborate as the glycosylation activator have been used in all of the glycosylation reactions throughout the synthetic scheme. The stereochemical outcomes of the glycosylations were excellent and the yields were very good.
synthesis, strain, polysaccharide, O-antigen, repeating unit, O antigen, cell, Escherichia, Escherichia coli, O-antigenic, O-antigenic polysaccharide, cell wall, pentasaccharide, linear, glycosyl, glycosylation, Synthetic, reaction, Glycosylations, outcome
Structure type: oligomer
Location inside paper: p.632, fig.1, compound 1
Aglycon: p-methoxyphenyl
Trivial name: repeating unit O-polysaccharide
Contained glycoepitopes: IEDB_130648,IEDB_136105,IEDB_137473,IEDB_1391961,IEDB_141584,IEDB_149549,IEDB_225177,IEDB_885822,IEDB_885823
Methods: 13C NMR, 1H NMR, IR, TLC, ESI-MS, MALDI-MS, chemical synthesis, chemical methods, glycosylation
Synthetic data: chemical
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G32784CP
Show glycosyltransferases
1H NMR data: present in publication
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13C NMR data: present in publication
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There is only one chemically distinct structure:
Found 
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