Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: urinary tract infections (UTI) [ICD11:
GC08 
];
infectious gastroenteritis [ICD11:
1A40.Z ]
The structure was elucidated in this paperNCBI PubMed ID: 25240185Publication DOI: 10.1016/j.carres.2014.07.008Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: yknirel
gmail.com (Y.A. Knirel)
Institutions: Department of Immunobiology of Bacteria, Institute of Microbiology, Biotechnology and Immunology, University of Lodz, PL 90-237 Lodz, Poland, TEDA School of Biological Sciences and Biotechnology, Nankai University, TEDA, 300457 Tianjin, PR China, N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
O-Polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of Providencia alcalifaciens O45:H25 and studied by sugar analysis, Smith degradation, and (1)H and (13)C NMR spectroscopy. The following structure of the pentasaccharide repeat of the O-polysaccharide was established: [structure: see text]. The O-antigen gene cluster of P. alcalifaciens O45 was sequenced and found to be in full agreement with the O-polysaccharide structure established.
Lipopolysaccharide, structure, gene, O-antigen, O antigen, cluster, gene cluster, O-polysaccharide, O polysaccharide, Providencia, Providencia alcalifaciens, bacterial polysaccharide structure, organization, O-antigen gene cluster
Structure type: polymer chemical repeating unit
Location inside paper: abstract, p.75, PS-1
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_115136,IEDB_135813,IEDB_136045,IEDB_137340,IEDB_140630,IEDB_141807,IEDB_142488,IEDB_142489,IEDB_144562,IEDB_145669,IEDB_146664,IEDB_150092,IEDB_151531,IEDB_152214,IEDB_174333,IEDB_490056,IEDB_983931,SB_192,SB_86
Methods: 13C NMR, 1H NMR, GLC-MS, NMR-2D, DNA sequencing, sugar analysis, GLC, mild acid hydrolysis, Smith degradation, de-O-acetylation, NMR-1D, GPC, function analysis of gene clusters
Related record ID(s): 30419, 30420
NCBI Taxonomy refs (TaxIDs): 126385Reference(s) to other database(s): GTC:G35874JB
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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