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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Coxiella burnetii [ICD11: XN0QS

]

Journal NLM ID: 7901356
WWW link: http://www.ichf.edu.pl/pjch/pj-1999/pj0799.htm#1055
Publisher: Państwowe Wydawnictwo Naukowe
Institutions: Research Center Borstel, Center for Medicine and Biosciences, 23845 Borstel, Germany

Lipopolysaccharides (LPS) consist of three regions, i.e. the lipid A, the core region, and the O-specific polysaccharide. The core region and the lipid A represent a common structural unit occurring in all LPS. The structures of the core region of various bacteria have been investigated intensively for the past ten years, and several core regions containing D-glycero-D-manno-heptose which is the biosynthetic precursor of the common core constituent L-glycero-D-manno-heptose have been identified. In this review, these core structures are summarized and briefly discussed.

Lipopolysaccharide, lipopolysaccharides, core, D-glycero-D-manno-heptose, composition, occurrence

Structure type: fragment of a bigger structure
Location inside paper: p.1064, table 5
Aglycon: lipid A
Compound class: core oligosaccharide
Contained glycoepitopes: IEDB_130650,IEDB_130659,IEDB_130701,IEDB_144983,IEDB_150901,IEDB_152206,IEDB_2189046,IEDB_983930,SB_44,SB_67,SB_72

Comments, role: review; incomplete structure of core region of LPS. The position of a side Man residue and DDHep linked to Hep I were not unequivocally identified (3 or 4).

NCBI Taxonomy refs (TaxIDs): 777
Reference(s) to other database(s): GTC:G86940HN
Show glycosyltransferases

There are 20 chemically distinct structures. Please, select:

O=C(O)[C@@]1(O)C[C@@H](O[C@]2(C(=O)O)C[C@@H](O[C@]3(C(=O)O)C[C@@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O3)[C@@H](O)[C@@H]([C@H](O)CO)O2)[C@@H](O[C@H]2O[C@H]([C@H](O)CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O[C@H]2O[C@H]([C@H](O)CO)[C@@H](O)[C@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]([C@H](O)CO)O1

SVG MW SMILES 3D mol Ionize