Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 21091983Journal NLM ID: 7703966Publisher: Japanese Society For Bacteriology
Correspondence: koma
hektor.umcs.lublin.pl
Institutions: Genetics and Microbiology Virology and Immunology, Maria Curie-Sklodowska University, Akademicka 19, 20-033 Lublin, Poland
The endotoxic activities of lipopolysaccharides (LPS) isolated from different strains of rhizobia and rhizobacteria (Bradyrhizobium, Mesorhizobium, and Azospirillum) were compared to those of Salmonella enterica sv. Typhimurium LPS. The biological activity of all the examined preparations, measured as Limulus lysate gelation, production of tumor necrosis factor (TNF), interleukin-1beta (IL-1β), and interleukin-6 (IL-6), and nitrogen oxide (NO) induction in human myelomonocytic cells (line THP-1), was considerably lower than that of the reference enterobacterial endotoxin. Among the rhizobial lipopolysaccharides, the activities of Mesorhizobium huakuii and Azospirillum lipoferum LPSs were higher than those of the LPS preparations from five strains of Bradyrhizobium. The weak endotoxic activity of the examined preparations was correlated with differences in lipid A structure compared to Salmonella.
Lipopolysaccharide, Rhizobium, endotoxin, cytokines
Structure type: oligomer
Location inside paper: p.720, fig.1, E. coli
Trivial name: lipid IVA
Compound class: LOS, lipid A, glycolipid
Contained glycoepitopes: IEDB_135394,IEDB_135515,IEDB_141807,IEDB_151531,IEDB_176772,IEDB_534864
Methods: SDS-PAGE, ELISA, statistical analysis, cytokines assay
Related record ID(s): 25309, 32007, 32008, 32009
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GlycomeDB:
7396
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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