Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 7697653Journal NLM ID: 0043535Publisher: Elsevier
Institutions: School of Pharmaceutical Sciences, Rhodes University, Grahamstown, 6140, Soth Africa, Department of Biochemistry, Imperial College of Science, Technology, and Medicine, London, SW7 2AZ, United Kingdom
Trideuteriomethylated and methylated derivatives of the capsular polysaccharide of Escherichia coli K57 were partially cleaved by Et3SiH, using Me3SiOSO2 Me and Me3SiOSO2CF3 as catalysts, to produce oligosaccharide-anhydroalditols. The structures of the trideuteriomethylated trisaccharide- and tetrasaccharide-anhydroalditols isolated were established by FABMS and NMR spectroscopy. Although conditions for the selective production of the tetrasaccharide-anhydroalditol could not be established, oligosaccharide-anhydroalditols were isolated in sufficiently high yield to make this an attractive approach for the structural elucidation of the repeating units of bacterial polysaccharides.
NMR, structure, capsular, polysaccharide, Escherichia, Escherichia coli, capsular polysaccharide, FAB MS, reductive cleavage, trideuteriomethylation
Structure type: polymer chemical repeating unit
Location inside paper: p.96
Compound class: CPS, O-polysaccharide, K-antigen
Contained glycoepitopes: IEDB_136044,IEDB_137340,IEDB_137472,IEDB_141794,IEDB_141807,IEDB_142078,IEDB_149136,IEDB_150899,IEDB_151531,IEDB_190606,SB_137,SB_165,SB_166,SB_187,SB_195,SB_29,SB_7,SB_88
Methods: NMR-2D, FAB-MS, NMR, reductive cleavage
Comments, role: published polymerization frame was shifted for conformity with other records.
Related record ID(s): 2995, 115915
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G76500PH, GlycomeDB:
5930
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error