Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Publication DOI: 10.1080/07388550500376166Journal NLM ID: 8505177Publisher: CRC Press
Correspondence: dzekovic
alltech.com
Institutions: Alltech's North American Bioscience Center, Nicholasville, KY, USA, Department of Chemistry, Institute of Chemistry, Technology and Metallurgy, Belgrade, Njegoševa 12, Montenegro, Faculty of Chemistry, Studentski trg 16, University of Belgrade, Belgrade, Serbia, Montenegro
A number of polysaccharides with β-glycosidic linkage are widespread in nature in a variety of sources. All have a common structure and the (1→3)-β-D-glucan backbone is essential. They have attracted attention over the years because of their bioactive and medicinal properties. In many cases their functional role is a mystery, in others it is well established. Because of their insoluble chemical nature, particulate (1→3)-β-D-glucans are not suitable for many medical applications. Various methods of changing or modifying the β-D-glucan chemical structure and transforming it to a soluble form have been published. The β-D-glucan bioactive properties can be affected positively or negatively by such modifications. This review examines β-glucan sources in nature, health effects and structure-activity relationships. It presents the current state of β-D-glucan solubilization methods and discusses their effectiveness and application possibilities for the future.
derivative, glucan, soluble, application, solubilization, Saccharomyces
Structure type: fragment of a bigger structure
Location inside paper: p.208, fig.1
Trivial name: β-1,3/1,6-glucan, lentinan, cell wall glucan, (1→3)-β-D-glucan
Compound class: EPS, cell wall polysaccharide, β-D-glucan, lentinan
Contained glycoepitopes: IEDB_1397514,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_241101,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Comments, role: review; The cell wall glucans of S. cerevisiae form major polysaccharide (1-3)-linked β-D-glucopyranosyl residues with small numbers of (1-6)-linked branches, and a minor component with consecutive (1-6)-linkages and (1-3)-branches.
Related record ID(s): 43702
NCBI Taxonomy refs (TaxIDs): 4932Reference(s) to other database(s): GTC:G70326NL
Show glycosyltransferases
There is only one chemically distinct structure:
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