Taxonomic group: fungi / Basidiomycota, Ascomycota, Ascomycota, Ascomycota, Ascomycota
(Phylum: Basidiomycota, Ascomycota, Ascomycota, Ascomycota, Ascomycota)
Organ / tissue: cell wallAssociated disease: infection due to Cryptococcus neoformans [ICD11:
XN3EH 
];
infection due to Paracoccidioides brasiliensis [ICD11:
XN5UX ];
infection due to Candida [ICD11:
XN3CL ]
NCBI PubMed ID: 26380326Publication DOI: 10.1155/2015/832057Journal NLM ID: 101627166Publisher: Cairo, Egypt: Hindawi Publishing Corporation
Correspondence: ana.trocoli
gmail.com
Institutions: Laboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, São Paulo, Brazil, Laboratório de Parasitologia Celular e Molecular, Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases.
cell wall, anti-cancer, inflammatory responses
Structure type: oligomer
Location inside paper: p. 7, column 1, paragraph 6
Trivial name: GlcCer
Contained glycoepitopes: IEDB_137339,IEDB_142488,IEDB_146664,IEDB_983931,SB_192,SB_5
Biological activity: elicits antibody responses in experimental infection models and patients affected by some mycoses; inhibits T-cell proliferation in vitro; ClcCer from A.fumigatus is able to activate in vitro moue and human NK cells and to induce airway heperreactivity in mice
Related record ID(s): 42330
NCBI Taxonomy refs (TaxIDs): 5207,
121759,
5476,
746128,
29908
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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