Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wall
NCBI PubMed ID: 26342143Publication DOI: 10.1016/j.sbi.2015.07.008Journal NLM ID: 9107784Publisher: Elsevier
Correspondence: jochen_zimmer

virginia.edu
Institutions: Center for Membrane Biology, Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, USA
Complex carbohydrates perform essential functions in life, including energy storage, cell signaling, protein targeting, quality control, as well as supporting cell structure and stability. Extracellular polysaccharides (EPS) represent mainly structural polymers and are found in essentially all kingdoms of life. For example, EPS are important biofilm and capsule components in bacteria, represent major constituents in cell walls of fungi, algae, arthropods and plants, and modulate the extracellular matrix in vertebrates. Different mechanisms evolved by which EPS are synthesized. Here, we review the structures and functions of membrane-integrated processive glycosyltransferases (GTs) implicated in the synthesis and secretion of chitin, alginate, hyaluronan and poly-N-acetylglucosamine (PNAG).
biosynthesis, cell wall, glycosyltransferases, polysaccharides, glycosylation, Metabolic engineering
Structure type: structural motif or average structure
Location inside paper: Fig. 3
Trivial name: chitin
Compound class: cell wall polysaccharide, glucan
Contained glycoepitopes: IEDB_135813,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_153212,IEDB_241099,IEDB_423114,IEDB_423150,SB_74,SB_85
Enzymes that release or process the structure: CHS1, CHS2
Biosynthesis and genetic data: biochemical data, genetic data
Synthetic data: enzymatic in vivo
Related record ID(s): 48511, 48512
NCBI Taxonomy refs (TaxIDs): 4932Reference(s) to other database(s): GTC:G97099AY
Show glycosyltransferases
There is only one chemically distinct structure: