Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: fruiting body
Publication DOI: 10.1007/978-3-319-16298-0_21Publisher: Springer International Publishing AG
Editors: Ramawat KG, Mérillon JM
Correspondence: Camelini CM <carla.maisa
gmail.com>; Sales-Campos C <ceci
inpa.gov.br>; Rossi MJ <marcio
enq.ufsc.br>; Gomes A <alinegomesfarma
gmail.com>; Giachini AJ <admir.giachini
gmail.com>; Cardozo FTGS <francielletg
gmail.com>
Institutions: Coordenação de Tecnologia e Inovação, Laboratório de cultivo de Fungos Comestíveis, Instituto Nacional de Pesquisas da Amazônia Universidade Federal do Amazonas, Manaus-AM, Brazil, Departamento de Microbiologia, Imunologia e Parasitologia, Laboratório de Bioprocessos, Universidade Federal de Santa Catarina, Florianópolis-SC, Brazil, Departamento de Moléstias Infecciosas e Parasitárias, Laboratório de Virologia, Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, Brazil
Many species of higher basidiomycetes have traditionally been used because of their medicinal properties. The positive effects associated to the consumption of those fungi have been mainly attributed to cell wall polysaccharides, which have important structural roles and are present throughout the entire life cycles of fungi. One of the most consumed and studied species native of the Americas is Agaricus subrufescens, a mushroom prescribed in different countries for prophylaxis and noninvasive treatment of numerous health-related disorders. Prior to the process of extraction, purification, and application of these polysaccharides, one needs to be concerned with the preservation of the specimen and production of fungal biomass. Even though basidiomata (syn. fruiting body, mushrooms) generally yield larger volumes of biomass when compared to the mycelium, cultivation of mycelium allows a more efficient control of the process and, therefore, is the method of choice of polysaccharide production. Mycelial biomass can be produced by solid-state fermentation (SSF) or submersed fermentation (SmF). Further separation and concentration of bioactive polysaccharides can be done by means of porous membranes, such as tangential flow nanofiltration.
polysaccharide, biological activity, Agaricus subrufescens, fungal biomass, solid-state fermentation (SSF), submersed fermentation (SmF), nanofiltration
Structure type: homopolymer
Location inside paper: Table 1
Trivial name: glucan, β-1,3-glucan, curdlan, curdlan-type polysaccharide 13140, paramylon, curdlan, laminarin, β-glucan, curdlan, β-(1,3)-glucan, β-(1,3)-glucan, curdlan, curdlan, β-1,3-glucan, paramylon, reserve polysaccharide, b-glucan, β-1,3-D-glucan, laminaran, botryosphaeran, laminaran type β-D-glucan, latiglucan I, pachymaran, Curdlan, zymosan A, β-glucan, curdlan, laminarin, zymosan, zymosan, glucan particles, zymosan, β-(1-3)-glucan, β-(1,3)-glucan, β-(1,3)glucan, pachymaran, D-glucan (DPn)540, pachyman, laminaran, curdlan, zymosan, zymosan, β-(1,3)-glucan, zymosan A, zymosan, β-1,3-glucan, curdlan, β-1,3-glucan, curdlan, β-1,3-glucan, curdlan, pachyman, β-(1,3)-glucan, curdlan, callose, a water-insoluble β-(1→3)-glucan, fermentum β-polysaccharide, water-insoluble glucan, alkali-soluble β-glucan (PeA3), alkali-soluble polysaccharide (PCAP), callose, laminarin
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, lipophosphoglycan, glycoprotein, LPG, glucan, polysaccharide, glycoside, β-glucan, β3-glucan, cell wall glucan
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Methods: extraction, dialysis, precipitation, centrifugation, HPLC-RI, DEAEС chromatography
Biological activity: inhibition of metastasizing capacity of cnacer cells(HT-29) in vitro
Related record ID(s): 42446, 42447, 42449, 42450
NCBI Taxonomy refs (TaxIDs): 79798Reference(s) to other database(s): GTC:G51056AN, GlycomeDB:
157, CCSD:
50049, CBank-STR:4225, CA-RN: 51052-65-4, GenDB:FJ3380871.1
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There is only one chemically distinct structure:
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