Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
The structure was elucidated in this paperNCBI PubMed ID: 20471414Publication DOI: 10.1016/j.ijbiomac.2010.05.006Journal NLM ID: 7909578Publisher: Butterworth-Heinemann
Correspondence: Yang R <yangronggya

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Institutions: Aesthetic and Plastic Surgery Center, Dermatology Diagnosis and Treatment Center of PLA, General Hospital of Beijing Military Region, Beijing, China, Hand Surgery Department, China-Japan Union Hospital of Jilin University, Changchun, China
Agaricus blazei polysaccharides were analyzed by GC-MS. Results indicated that the polysaccharides contained glucose (93.87%), mannose (3.54%), and arabinose (2.25%). The compositional analysis was completed by the methylation data. These data indicated that Agaricus blazei polysaccharides are glucans. Compared to model rats, rats fed with Agaricus blazei polysaccharides showed a decrease of ratio of IL-1β/β-actin and IL-1β level in skin of burn wound. Recovery rate of wound skin increased with increasing dose of polysaccharides. The results indicated that Agaricus blazei polysaccharides could be useful in promote burn wound healing.
rat, skin, GC–MS, Agaricus blazei polysaccharides, IL-1β
Structure type: structural motif or average structure
Location inside paper: p. 156, column 2, paragraph 2, AgHWE, AgCA, AgHA
Trivial name: β-1,6-glucan
Compound class: EPS, cell wall polysaccharide, glucan
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Methods: PCR, GC-MS, ELISA, UV, methylation analysis, ANOVA
Biological activity: application on burn injury increases the percentage of wound contraction, which indicates rapid epithelization and collagenization; decreases the level of IL-1β in a dose-dependent manner
NCBI Taxonomy refs (TaxIDs): 79798Reference(s) to other database(s): GTC:G26777BZ
Show glycosyltransferases
There is only one chemically distinct structure: