Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: sclerotium
Publication DOI: 10.1016/j.carbpol.2011.03.052Journal NLM ID: 8307156Publisher: Elsevier
Correspondence: Wang Y <river0301
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Institutions: Key Laboratory of Agricultural Products Chemical and Biological Processing Technology of Zhejiang Province, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China
Water-insoluble (1-3)-β-D-glucan isolated from the sclerotium of P. cocos exhibits little physiological activity. Therefore, it is advantageous to produce a value-added product from P. cocos. Extracted from the sclerotium of P. cocos, the (1-3)-β-D-glucan was oxidized by using TEMPO/NaBr/NaClO oxidation system and the water-soluble oxidized product was prepared. The structural and physiological properties of the derivative were investigated. The composition of the oxidized product was confirmed by Fourier transform infrared spectroscopy, the molecular weight parameters were obtained by LLS analysis. The oxidation caused the enhancement of in vitro bile acid binding capacity of the polysaccharides which would be explained by the improved water solubility and structural changes caused by oxidation. In addition, in vitro hydroxyl radical scavenging activity of the derivative was observed.
oxidation, bile acid, P. cocos, TEMPO, hydroxyl radical scavenging activity
Structure type: homopolymer ; 123000
Location inside paper: (1-3)-β-D-glucan, fig. 1
Trivial name: β-1,3-D-glucan
Compound class: glucan
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Methods: FTIR, TEMPO oxidation, laser light scattering, NaClO oxidation
Biological activity: bile acid binding capacity of (1-3)-β-D-glucan is 9.31 (μM/mg, dry matter)
Related record ID(s): 42689
NCBI Taxonomy refs (TaxIDs): 81056Reference(s) to other database(s): GTC:G51056AN
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There is only one chemically distinct structure:
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(later renamed to: Wolfiporia cocos)