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Taxonomic group: fungi / Ascomycota (Phylum: Ascomycota)
Organ / tissue: cell wall
Associated disease: sporotrichosis [ICD11: 1F2J

, ICD11: XN6GM

]; infection due to Sporothrix schenckii [ICD11: XN6GM

]

The structure was elucidated in this paper
NCBI PubMed ID: 4822869
Publication DOI: 10.1021/bi00656a028
Journal NLM ID: 0246127
Publisher: American Society for Microbiology
Institutions: Prairie Regional Laboratory, National Research Council, Saskatoon, SK, Canada, Departments of Dermatology and Biochemistry, College of Physicians and Surgeons, Columbia University, New York, USA

The proton and (13)C magnetic resonance (CMR) spectra of 10 Sporothrix schenckii and three Ceratocystis stenoceras rhamnomannans were studied. On the basis of their CMR spectra, the rhamnomannans from S. schenckii strains could be classified into two major types, I and II, readily distinguishable from the polysaccharides formed at the same temperature (25 C) by C. stenoceras. Rhamnomannans from S. schenckii synthesized at 37 C gave CMR spectra (type III) differing from those of polysaccharides of types I and II and from those of C. stenoceras polysaccharides. The contention that C. stenoceras might be the perfect form of S. schenckii is not supported by the present data. A presumptive pathogenic mutant of C. stenoceras synthesized a type I rhamnomannan characteristic of S. schenckii, clearly differing from the rhamnomannans from C. stenoceras synthesized in the same conditions. Nuclear magnetic resonance spectroscopy revealed differences in the structures of the polysaccharides from these species not previously recognized by methylation analysis.

NMR, Sporothrix schenckii, Ceratocystis stenoceras

Structure type: structural motif or average structure
Location inside paper: fig.3, table 1, table 2, table 3, fig.1, fig.2
Compound class: EPS, cell wall polysaccharide, rhamnomannan
Contained glycoepitopes: IEDB_130701,IEDB_133754,IEDB_136105,IEDB_140116,IEDB_141793,IEDB_141828,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_225177,IEDB_76933,IEDB_885823,IEDB_983930,SB_198,SB_44,SB_67,SB_72

Methods: 13C NMR, 1H NMR, GLC, methylation analysis, cell growth, precipitation

Related record ID(s): 43422, 43423, 43424, 43425, 43429, 43434
NCBI Taxonomy refs (TaxIDs): 29908, 1397361, 5173
Reference(s) to other database(s): GTC:G13333EQ
Show glycosyltransferases

NMR conditions: in D2O at 343 K

¹H NMR data: present in publication

¹³C NMR data: present in publication

There is only one chemically distinct structure:

*OC[C@H]1O[C@H](*)[C@@H](O)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H]1O

SVG MW SMILES 3D mol Ionize