Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wallAssociated disease: sporotrichosis [ICD11:
1F2J 
, ICD11:
XN6GM ];
infection due to Sporothrix schenckii [ICD11:
XN6GM ]
NCBI PubMed ID: 22203817Publication DOI: 10.3389/fmicb.2011.00243Journal NLM ID: 101548977Publisher: Lausanne: Frontiers Research Foundation
Correspondence: leila
uerj.br; leila.lopes_bezerra
pq.cnpq.br
Institutions: Laboratório de Micologia Celular e Proteômica, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil
This mini-review article is dedicated to clarifying certain important biochemical aspects of Sporothrixschenckii cell wall peptidorhamnomannans. Cell wall components involved in the host interaction such as antigens as well as a gp70 adhesin are important molecules present on the surface of the yeast parasitic phase. Other structural glycoconjugates present on the fungus cell surface are also described here. Knowledge of the fine structure of carbohydrate epitopes expressed on the surface in both morphological phases of S. schenckii permitted the development of non-invasive immunochemical methods to diagnose human and feline sporotrichosis.
antigens, cell wall, Sporothrix schenckii, gp70, peptidorhamnomannan
Structure type: structural motif or average structure
Location inside paper: fig.1 B
Aglycon: internal core (->3) L-Asn-Xxx-L-Ser/L-Thr (protein)
Compound class: rhamnomannan
Contained glycoepitopes: IEDB_130701,IEDB_133754,IEDB_136105,IEDB_140116,IEDB_141793,IEDB_141828,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_225177,IEDB_76933,IEDB_885823,IEDB_983930,SB_198,SB_44,SB_67,SB_72
Comments, role: aLRhap(1-2)aLRhap(1-3) epitope is characteristic of the mycelial life stage; aLRhap(1-3) epitope is characteristic of the both mycelial and yeast life stage
Related record ID(s): 43489, 43490, 48787
NCBI Taxonomy refs (TaxIDs): 29908Reference(s) to other database(s): GTC:G17985RY
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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