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Taxonomic group: fungi / Basidiomycota (Phylum: Basidiomycota)
Organ / tissue: capsule
Associated disease: infection due to Cryptococcus neoformans [ICD11: XN3EH

]; infection due to Cryptococcus gattii [ICD11: XN0LE

]

NCBI PubMed ID: 12912884
Publication DOI: 10.1128/EC.2.4.655-663.2003
Journal NLM ID: 101130731
Publisher: American Society for Microbiology
Correspondence: Doering TL <doering

borcim.wustl.edu>
Institutions: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA, Unité de Mycologie Moléculaire, Institut Pasteur, Paris Cedex, France

(no abstract)

Cryptococcus neoformans, Glucuronoxylomannan

Structure type: suggested polymer biological repeating unit
Location inside paper: fig. 2 (structure A), GXM
Trivial name: glucuronoxylomannan (GXM), glucuronoxylomannan
Compound class: CPS, EPS, O-polysaccharide, O-antigen, cell wall polysaccharide, polysaccharide, glucuronoxylomannan, capsule polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_115136,IEDB_115576,IEDB_130701,IEDB_140116,IEDB_140630,IEDB_144983,IEDB_145668,IEDB_152206,IEDB_164174,IEDB_167188,IEDB_174332,IEDB_2270799,IEDB_423153,IEDB_76933,IEDB_983930,SB_197,SB_44,SB_67,SB_72

Comments, role: Review. Сhemical repeating unit frame was shifted in annotation for compatibility with structures elucidated by MS [Eukaryotic Cell 2007, 6: 1464-1473]

Related record ID(s): 43588
NCBI Taxonomy refs (TaxIDs): 37769
Reference(s) to other database(s): GTC:G42955PN
Show glycosyltransferases

There is only one chemically distinct structure:

*O[C@H]1[C@H](O[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@@H](CO)O[C@H](O[C@@H]2[C@H](O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O[C@H]3[C@H](O)[C@@H](CO)O[C@H](*)[C@H]3O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)O[C@H](CO)[C@H]2O)[C@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O

SVG MW SMILES 3D mol Ionize