Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: capsuleAssociated disease: infection due to Cryptococcus neoformans [ICD11:
XN3EH 
]
The structure was elucidated in this paperNCBI PubMed ID: 7028261Publication DOI: 10.1016/S0008-6215(00)85580-9Journal NLM ID: 0043535Publisher: Elsevier
Institutions: National Institute of Arthritis, Metabolism, and Digestive Diseases and Kidney, National Institutes of Health, Bethesda, USA, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
The capsular polysaccharides from Cryptococcus neoformans serotype A and from a possible, mutant strain thereof have been structurally analyzed. The latter material is similar to the capsular antigen of C. neoformans serotype D.
carbohydrates, immunology, Bacterial polysaccharide, serotyping, Cryptococcus neoformans, cryptococcosis
Structure type: suggested polymer biological repeating unit
Location inside paper: p.245, structure 2, 3, fig.4 (b)
Trivial name: glucuronoxylomannan (GXM)
Compound class: CPS, EPS, O-polysaccharide, O-antigen, cell wall polysaccharide, polysaccharide, glucuronoxylomannan, capsule polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_115136,IEDB_115576,IEDB_130701,IEDB_140116,IEDB_140630,IEDB_144983,IEDB_145668,IEDB_152206,IEDB_164174,IEDB_167188,IEDB_174332,IEDB_2270799,IEDB_423153,IEDB_76933,IEDB_983930,SB_197,SB_44,SB_67,SB_72
Methods: 13C NMR, methylation, GLC-MS, deacetylation, GLC, alkaline degradation, Smith degradation, paper chromatography, immunodiffusion assays, optical rotation measurement, reduction, hydrolysis, CC, evaporation
Comments, role: chemical repeating unit frame was shifted in annotation for compatibility with structures elucidated by MS [Eukaryotic Cell 2007, 6: 1464-1473]
Related record ID(s): 40815, 42129, 43807, 43815
NCBI Taxonomy refs (TaxIDs): 178876Reference(s) to other database(s): GTC:G75580HK, CCSD:
50376, CBank-STR:15059
Show glycosyltransferases
NMR conditions: in D2O at 343(C) K
[as TSV]
13C NMR data: present in publication
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There is only one chemically distinct structure:
Found 
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(later renamed to: Cryptococcus neoformans var. grubii 371-3)