Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: capsuleAssociated disease: infection due to Cryptococcus neoformans [ICD11:
XN3EH 
];
infection due to Cryptococcus gattii [ICD11:
XN0LE ]
The structure was elucidated in this paperNCBI PubMed ID: 387576Publication DOI: 10.1016/0161-5890(79)90081-6Journal NLM ID: 7905289Publisher: Elsevier
Institutions: National Institute of Arthritis, Metabolism, and Digestive Diseases and Kidney, National Institutes of Health, Bethesda, USA, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
Further examination of the capsular polysaccharide of Cryptococcus neoformans serotype C by alkaline degradation and methylation, followed by hydrolysis, has shown that the glucuronic acid residues in the polysaccharides are located on the mannose residue already substituted with xylose. In addition, the anomeric configuration of the sugars has been confirmed by 1H NMR spectroscopy
carbohydrates, immunology, Bacterial polysaccharide, serotyping, Cryptococcus neoformans, cryptococcosis, glucuronates
Structure type: suggested polymer biological repeating unit
Location inside paper: p.532, structure 2
Trivial name: glucuronoxylomannan (GXM)
Compound class: CPS, EPS, O-polysaccharide, O-antigen, cell wall polysaccharide, polysaccharide, glucuronoxylomannan, capsule polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_115136,IEDB_115576,IEDB_130701,IEDB_140116,IEDB_140630,IEDB_144983,IEDB_145668,IEDB_152206,IEDB_164174,IEDB_167188,IEDB_174332,IEDB_2270799,IEDB_423153,IEDB_76933,IEDB_983930,SB_197,SB_44,SB_67,SB_72
Methods: 1H NMR, methylation, GC-MS, acid hydrolysis, alkaline degradation, GC
Comments, role: chemical repeating unit frame was shifted in annotation for compatibility with structures elucidated by MS [Eukaryotic Cell 2007, 6: 1464-1473]
Related record ID(s): 40817, 43809, 43817, 43823
NCBI Taxonomy refs (TaxIDs): 37769Reference(s) to other database(s): GTC:G39597XD
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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(later renamed to: Cryptococcus gattii VGI C)