Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: capsuleAssociated disease: infection due to Cryptococcus neoformans [ICD11:
XN3EH 
]
The structure was elucidated in this paperNCBI PubMed ID: 113098Publication DOI: 10.1016/S0008-6215(00)85488-9Journal NLM ID: 0043535Publisher: Elsevier
Institutions: National Institute of Arthritis, Metabolism, and Digestive Diseases and Kidney, National Institutes of Health, Bethesda, USA, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
The capsular polysaccharide from Cryptococcus neoformans serotype D has been studied by employing the usual methods for the elucidation of chemical structure. The results are consistent with the occurrence of a polysaccharide having both D-glucosyl-uronic acid and D-xylosyl groups present as nonreducing end-groups attached to O-2 of D-mannosyl residues which are linked α-D-(1→3) in a linear backbone.
carbohydrates, immunology, Bacterial polysaccharide, serotyping, Cryptococcus neoformans, cryptococcosis
Structure type: suggested polymer biological repeating unit
Location inside paper: fig.4, structure, p.190
Trivial name: glucuronoxylomannan (GXM)
Compound class: CPS, EPS, O-polysaccharide, O-antigen, cell wall polysaccharide, polysaccharide, glucuronoxylomannan, capsule polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_115136,IEDB_115576,IEDB_130701,IEDB_140116,IEDB_140630,IEDB_144983,IEDB_145668,IEDB_152206,IEDB_164174,IEDB_167188,IEDB_174332,IEDB_423153,IEDB_76933,IEDB_983930,SB_197,SB_44,SB_67,SB_72
Methods: 1H NMR, methylation, periodate oxidation, GLC-MS, acid hydrolysis, GLC, Smith degradation, paper chromatography, electrophoresis, ion-exchange chromatography, quantification of O-acetylation, optical rotation measurement, autohydrolysis, chromium trioxide oxidation, reduction, CC
Comments, role: chemical repeating unit frame was shifted in annotation for compatibility with structures elucidated by MS [Eukaryotic Cell 2007, 6: 1464-1473]
NCBI Taxonomy refs (TaxIDs): 40410Reference(s) to other database(s): GTC:G53406VG
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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(later renamed to: Cryptococcus neoformans var. neoformans B-3502)