Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
Publication DOI: 10.1021/jo961668sJournal NLM ID: 2985193RPublisher: Columbus, OH: American Chemical Society
Institutions: Paul M. Gross Chemical Laboratory, Department of Chemistry, Duke University, Durham, North Carolina 27708, and Natural Products and Glycotechnology Research Institute, Inc. (NPG), Durham, North Carolina 27707
Disaccharides containing two glucosamine units are readily synthesized where the two amine functionalities are orthogonally protected as the tetrachlorophthaloyl and pent-4-enoyl moieties. The 1f6 linked disaccharide has the potential to be developed toward a series of biologically interesting lipid A analogs.
synthesis, structure, lipid, lipid A, endotoxin, fragment, disaccharide, lipids, disaccharides
Structure type: oligomer
Location inside paper: p.3655, fig.1, compound 1
Trivial name: lipid IVA
Compound class: LOS, lipid A, glycolipid
Contained glycoepitopes: IEDB_135394,IEDB_135515,IEDB_141807,IEDB_151531,IEDB_176772,IEDB_534864
Methods: 13C NMR, 1H NMR, FAB-MS, TLC, chemical synthesis, chemical methods
Comments, role: (synthesis)
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GlycomeDB:
7396
Show glycosyltransferases
There is only one chemically distinct structure: