Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Associated disease: infection due to Aspergillus fumigatus [ICD11:
XN5Z7 
]
NCBI PubMed ID: 18686165Publication DOI: 10.1080/13693780802258832Journal NLM ID: 9815835Publisher: Oxford: Oxford University Press
Correspondence: jplatge
pasteur.fr
Institutions: Institut Pasteur, Aspergillus Unit, Paris, France
Galactofuranose is a major carbohydrate in Aspergillus fumigatus. It became famous in medical mycology as being part of the galactomannan which was shown 30 years ago to be the major antigen circulating in the body fluid of patients suffering from invasive aspergillosis. Four different molecules contain galactofuranose in A. fumigatus: (i) the galactomannan present in the alkali soluble and insoluble fraction of the cell wall (ii) N- and O glycan moieties of secreted glycoproteins (iii) a GPI- anchored lipophosphogalactomannan and (iv) several sphingolipids also anchored to the membrane by an inositol phosphoceramide.
genetics, cell wall, glycobiology, Aspergillus, aspergillosis
Structure type: oligomer
Location inside paper: Table 1 (entry 3)
Compound class: GPI-anchor
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_164174,IEDB_983930,SB_136,SB_196,SB_197,SB_44,SB_67,SB_72
Comments, role: absolute D-configurations and pyranose ring sizes were assumed by CSDB staff
Related record ID(s): 44542, 44543, 44544, 44545, 44547, 44548, 44549, 44550, 44551, 44552, 44553, 44554, 44555
NCBI Taxonomy refs (TaxIDs): 746128
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error
(previously named: Sartorya fumigata, Aspergillus fumigates, Neosartorya fumigata)