Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota) Associated disease: infection due to Aspergillus fumigatus [ICD11:
XN5Z7 ]
NCBI PubMed ID: 18686165 Publication DOI: 10.1080/13693780802258832 Journal NLM ID: 9815835 Publisher: Oxford: Oxford University Press
Correspondence: jplatge
pasteur.fr
Institutions: Institut Pasteur, Aspergillus Unit, Paris, France
Galactofuranose is a major carbohydrate in Aspergillus fumigatus. It became famous in medical mycology as being part of the galactomannan which was shown 30 years ago to be the major antigen circulating in the body fluid of patients suffering from invasive aspergillosis. Four different molecules contain galactofuranose in A. fumigatus: (i) the galactomannan present in the alkali soluble and insoluble fraction of the cell wall (ii) N- and O glycan moieties of secreted glycoproteins (iii) a GPI- anchored lipophosphogalactomannan and (iv) several sphingolipids also anchored to the membrane by an inositol phosphoceramide.
genetics, cell wall, glycobiology, Aspergillus, aspergillosis
Structure type: structural motif or average structure
Location inside paper: Fig. 6III
Compound class: GPI-anchor
Contained glycoepitopes: IEDB_130701,IEDB_133966,IEDB_136104,IEDB_137485,IEDB_141793,IEDB_141807,IEDB_143632,IEDB_144983,IEDB_144995,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_164174,IEDB_164479,IEDB_983930,SB_136,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
Comments, role: absolute D-configurations and pyranose ring sizes were assumed by CSDB staff
Related record ID(s): 44542, 44543, 44544, 44545, 44546, 44547, 44548, 44549, 44550, 44551, 44552, 44553, 44555
NCBI Taxonomy refs (TaxIDs): 746128
Show glycosyltransferases
There are 32 chemically distinct structures. Please, select:
?DManp(1-2)?DManp(1-2)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-2)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-2)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-2)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-3)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-3)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-3)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-3)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-4)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-4)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-4)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-4)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-6)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-6)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-6)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-6)aDGlcpN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-2)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-2)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-2)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-2)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-3)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-3)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-3)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-3)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-5)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-5)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-5)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-5)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-2)?DManp(1-6)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-3)?DManp(1-6)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-4)?DManp(1-6)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
?DManp(1-6)?DManp(1-6)aDGlcfN(1-2)xLmyoIno?(1-P-1)CER
Found 
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(previously named: Sartorya fumigata, Aspergillus fumigates, Neosartorya fumigata)
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