Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wall,
mother-bud neck
NCBI PubMed ID: 23949603Publication DOI: 10.1038/nrmicro3090Journal NLM ID: 101190261Publisher: London, UK: Nature Publishing Group
Correspondence: Cabib E <enricoc
bdg10.niddk.nih.gov>
Institutions: Laboratory of Biochemistry and Genetics, National institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, USA, the Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias, Madrid, Spain
In budding yeast, the neck that connects the mother and daughter cell is the site of essential functions such as organelle trafficking, septum formation and cytokinesis. Therefore, the morphology of this region, which depends on the surrounding cell wall, must be maintained throughout the cell cycle. Growth at the neck is prevented, redundantly, by a septin ring inside the cell membrane and a chitin ring in the cell wall. Here, we describe recent work supporting the hypothesis that attachment of the chitin ring, which forms at the mother–bud neck during budding, to β-1,3-glucan in the cell wall is necessary to stop growth at the neck. Thus, in this scenario, chemistry controls morphogenesis.
Structure type: polymer chemical repeating unit
Location inside paper: p. 648, column 3, paragraph 3
Trivial name: pustulan, β-1,6-glucan, β-(1,6)-glucan
Compound class: CPS, cell wall polysaccharide, glucan
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Enzymes that release or process the structure: Crh1, Crh2
Comments, role: attached to β-1,3-glucan
Related record ID(s): 44858, 44888, 44939, 47842, 47843, 48303, 48366, 48412, 48423, 48443, 49291, 50093
NCBI Taxonomy refs (TaxIDs): 4932Reference(s) to other database(s): GTC:G26777BZ, GlycomeDB:
863
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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