Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
The structure was elucidated in this paperPublication DOI: 10.1248/cpb.38.1745Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Tokyo College of Pharmacy, Tokyo, Japan, The Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan
Analytical data of Smith-type degradation products and carbon-13 nuclear magnetic resonance spectroscopy of an alkali-soluble glucan, OL-2, which was isolated from a crude fungal drug "Leiwan" (Omphalia lapidescens), suggested that OL-2 was a β-1,3-D-glucan possessing approximately two branches at every three main chain glucosyl unit at each C-6 position. Antitumor activities of OL-2 and the degradation product, OR-OL-2c, against the solid form of sarcoma 180 in ICR mice were negative.
methylation analysis, 3-D-glucan, leiwan (Omphalia lapidescens), 6-O-branched β-1, Smith-type degradation
Structure type: homopolymer ; 50000
Location inside paper: Fig.1, structure C, OR-OL-2c
Trivial name: curdlan
Compound class: O-polysaccharide, glucan
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Methods: 13C NMR, methylation, periodate oxidation, GLC-MS, IR, TLC, acid hydrolysis, GLC, Smith degradation, extraction, reduction, antitumor activity assay, Congo Red assay
Biological activity: Glucan does not show inhibition of the sarcoma 180 tumor cells growth.
Related record ID(s): 41552, 41631, 41632, 45733, 45735, 50617, 50648, 50654, 50665, 50671, 50861
NCBI Taxonomy refs (TaxIDs): 2962918Reference(s) to other database(s): GTC:G51056AN
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There is only one chemically distinct structure:
Found 
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(later renamed to: Gerronema lapidescens)