Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Host organism: Helianthus annuus
Associated disease: Verticillium wilt
NCBI PubMed ID: 19962895Publication DOI: 10.1016/j.bmcl.2009.11.063Journal NLM ID: 9107377Publisher: Elsevier
Correspondence: Hashimoto M <hmasaru
cc.hirosaki-u.ac.jp>
Institutions: Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan, Graduate School of Health Sciences, Hirosaki University, Hirosaki, Japan
Novel fusapyrone analogs, deoxyneofusapyrone and 7-desmethyldeoxyneofusapyrone were isolated from a pathogenic fungus, Verticillium dahliae, which causes Verticillium wilt disease in Helianthus annuus. Spectral analyses revealed that these are 2-pyrone type analogs of deoxyfusapyrone and its 7-desmethyl derivative, respectively. Biological assay disclosed that 10microg of deoxyneofusapyrone inhibited the growth of MRSA clinical isolate 87-7927.
isolation and structure determination, NMR spectral analysis, 4-hydroxy-2-pyrone, IR spectra, theoretical 13C NMR chemical shift, inhibition of MRSA clinical isolate 87-7927
Structure type: monomer
Location inside paper: Fig.1, structure 4
Trivial name: deoxyfusapyrone
Compound class: glycoside
Methods: 13C NMR, 1H NMR, IR, biological assays, HPLC, UV, optical rotation measurement, CC, cell growth, HR-ESI-MS, HMBC, evaporation, NOESY
Related record ID(s): 46012, 46014, 46015, 46016, 46021
NCBI Taxonomy refs (TaxIDs): 27337
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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