Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
NCBI PubMed ID: 25992423Journal NLM ID: 101230869Publisher: Stevenson Ranch, CA: American Scientific Publishers
Correspondence: Azuma K <kazu-azuma

muses.tottori-u.ac.jp>; Ifuku S <sifuku

chem.tottori-u.ac.jp>
Institutions: Faculty of Agriculture, Tottori University, Tottori, Japan, Graduated School of Engineering, Tottori University, Tottori, Japan
Chitin (β-(1-4)-poly-N-acetyl-D-glucosamine) is widely distributed in nature and is the second most abundant polysaccharide after cellulose. Chitin occurs in nature as ordered macrofibrils. It is the major structural component in the exoskeleton of crab and shrimp shells and the cell wall of fungi and yeast. As chitin is not readily dissolved in common solvents, it is often converted to its more deacetylated derivative, chitosan. Chitin, chitosan, and its derivatives are widely used in tissue engineering, wound healing, and as functional foods. Recently, easy methods for the preparation of chitin and chitosan nanofibers have been developed, and studies on biomedical applications of chitin and chitosan nanofibers are ongoing. Chitin and chitosan nanofibers are considered to have great potential for various biomedical applications, because they have several useful properties such as high specific surface area and high porosity. This review summarizes methods for the preparation of chitin and chitosan nanofibers. Further, biomedical applications of chitin and chitosan nanofibers in (i) tissue engineering, (ii) wound dressing, (iii) cosmetic and skin health, (iv) stem cell technology, (v) anti-cancer treatments and drug delivery, (vi) anti-inflammatory treatments, and (vii) obesity treatment are summarized. Many studies indicate that chitin and chitosan nanofibers are suitable materials for various biomedical applications.
drug delivery, cosmetics, chitosan, chitin, obesity, nanofibers, biomedical applications, tissue engineering, stem cells
Structure type: homopolymer
Location inside paper: abstract
Trivial name: chitin
Compound class: O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide, chitin
Contained glycoepitopes: IEDB_135813,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_153212,IEDB_241099,IEDB_423114,IEDB_423150,SB_74,SB_85
Related record ID(s): 40517, 43385, 101632, 118702, 139869, 143703, 145244, 147175, 149428, 149871, 149874
NCBI Taxonomy refs (TaxIDs): 5323,
5341,
5353,
5627,
39966Reference(s) to other database(s): GTC:G97099AY, CCSD:
46067, CBank-STR:5851, GenDB:KF905651
Show glycosyltransferases
There is only one chemically distinct structure: