Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
NCBI PubMed ID: 25353009Publication DOI: 10.3389/fcimb.2014.00145Journal NLM ID: 101585359Publisher: Lausanne: Frontiers Media SA
Correspondence: Barreto-Bergter E <eliana.bergter
micro.ufrj.br>; Figueiredo RT <rotifi
icb.ufrj.br>
Institutions: Departamento de Microbiologia Geral, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Instituto de Ciências Biomédicas/Unidade de Xerém, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Departamento de Microbiologia Geral, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil, Instituto de Ciências Biomédicas/Unidade de Xerém, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil
Polysaccharides such as α- and β-glucans, chitin, and glycoproteins extensively modified with both N- and O-linked carbohydrates are the major components of fungal surfaces. The fungal cell wall is an excellent target for the action of antifungal agents, since most of its components are absent from mammalian cells. Recognition of these carbohydrate-containing molecules by the innate immune system triggers inflammatory responses and activation of microbicidal mechanisms by leukocytes. This review will discuss the structure of surface fungal glycoconjugates and polysaccharides and their recognition by innate immune receptors.
glycoconjugates, polysaccharides, innate immunity, fungal pathogens, pattern recognition receptors
Structure type: homopolymer
Location inside paper: p. 5, column 1, line 12, section ''FUNGAL GLYCOCONJUGATES AND POLYSACCHARIDES; CHITIN''
Trivial name: chitin
Compound class: O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide, chitin
Contained glycoepitopes: IEDB_135813,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_153212,IEDB_241099,IEDB_423114,IEDB_423150,SB_74,SB_85
Methods: 13C NMR, 1H NMR, GC-MS, ESI-MS, TOCSY, methylation analysis, HMQC
Comments, role: Review.
Related record ID(s): 40517, 43385, 45260, 45262, 45281, 45287, 45290, 46294, 46295, 46296, 46297, 46298, 46299, 46300, 46301, 46302, 46303, 101632, 118702, 139869, 143703, 145244, 147175, 149428, 149871, 149874
NCBI Taxonomy refs (TaxIDs): 4932,
746128Reference(s) to other database(s): GTC:G97099AY, CCSD:
46067, CBank-STR:5851, GenDB:KF905651
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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