Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Associated disease: infection due to Candida [ICD11:
XN3CL 
]
Publication DOI: 10.1016/S0040-4020(01)01087-0Journal NLM ID: 2984170RPublisher: Pergamon Press
Correspondence: dcrich
uic.edu
Institutions: Department of Chemistry, University of Illinois at Chicago, Chicago, IL, USA, Instituto de Quı́mica, Universidad Nacional Autónoma de México Circuito Exterior, Ciudad Universitaria, Coyoacán, Mexico
The total synthesis of the two possible diastereomers of mannosylerythritol lipid A, a novel biosurfactant from Candida antartica T-34 with promising anti-proliferative properties in several cell lines, is described. By comparison with an authentic sample, the natural material is confirmed as a single diastereomer with the 4-O-(β-D-mannopyranosyl) D-erythritol configuration. The configuration of the mannosyl erythritol lipids is confirmed by total synthesis as 4-O-(β-D-mannopyranosyl) D-erythritol
biosurfactant, mannosyl erythritol lipid, meso-erythritol
Structure type: monomer
Location inside paper: p. 36, structure 3
Compound class: glycolipid
Contained glycoepitopes: IEDB_114707,IEDB_137485,IEDB_144983,IEDB_152206,IEDB_983930,SB_44,SB_72
Methods: 13C NMR, 1H NMR, chemical synthesis, optical rotation measurement, elemental analysis, HR-ESI-MS
Comments, role: LIP is C8-C14
Related record ID(s): 47845, 47846, 47847, 47849, 47850, 49346, 49347, 49348
NCBI Taxonomy refs (TaxIDs): 5269,
5475Reference(s) to other database(s): GTC:G76561UM
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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