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Taxonomic group: fungi / Ascomycota (Phylum: Ascomycota)
Organ / tissue: cell wall
Associated disease: infection due to Aspergillus [ICD11: XN0WC

]

Publication DOI: 10.1007/978-4-431-55248-2_10
Publisher: Springer, Tokyo
Editors: Takagi H, Kitagaki H
Correspondence: mgoto

brs.kyushu-u.ac.jp
Institutions: Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan, Department of Applied Microbial Technology, Faculty of Biotechnology and Life Science, Sojo University, Kumamoto, Japan, Education and Research Center for Fermentation Studies, Faculty of Agriculture, Kagoshima University, Kagoshima, Japan

The cell wall provides physical strength to cells and defines the morphology of fungi. During hyphal development of filamentous fungi, the apical region and the branching sites of the cell are remodeled to support hyphal extension and formation of a new hypha. The cell wall has contact with the environment and thus is the place of first contact with external stresses originating outside of the cells. The cell wall also acts as a matrix for various extracellular proteins such as enzymes and sensor proteins. Budding yeast (Saccharomyces cerevisiae) and filamentous fungi (Aspergillus species) are industrially and medically important fungi belonging to the Ascomycota. These fungi share similar composition in the cell wall although they are morphologically different. Fungal cell walls are usually composed of glucose, mannose, N-acetyl-D-glucosamine, proteins, and lipids. Some glycans composed of galactofuranose or N-acetyl-D-galactosamine are found characteristically in the cell wall of Aspergillus species. In this chapter, we present an overview of current knowledge on cell wall biogenesis and wall-stress sensing in fungi, particularly focusing on recent findings in filamentous fungi

cell wall, glycosylation, Glucans, Aspergillus, fungi, GPI anchor, Saccharomyces, cell wall integrity, stress response

Structure type: oligomer
Location inside paper: Fig. 10.2, N-glycans, top structure
Aglycon: protein
Compound class: N-glycan, glucomannan
Contained glycoepitopes: IEDB_130701,IEDB_135813,IEDB_136104,IEDB_137340,IEDB_137485,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141807,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_149158,IEDB_151079,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_164174,IEDB_164480,IEDB_233377,IEDB_429156,IEDB_76933,IEDB_857734,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_53,SB_67,SB_72,SB_73,SB_77

Related record ID(s): 48413, 48415, 48416, 48417, 48418, 48419, 48420, 48421
NCBI Taxonomy refs (TaxIDs): 5052
Show glycosyltransferases

There is only one chemically distinct structure:

CC(=O)N[C@H]1[C@H](O[C@@H]2[C@@H](CO)O[C@@H](NC(=O)C[C@H](N)C(=O)O)[C@H](NC(C)=O)[C@H]2O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO[C@H]3O[C@H](CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@@H]1O

SVG MW SMILES 3D mol Ionize

Warning = sub-repeat ending at aDManp: variable unit count (0-2) was assumed to be 0