Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: capsuleAssociated disease: infection due to Cryptococcus neoformans [ICD11:
XN3EH 
];
infection due to Cryptococcus gattii [ICD11:
XN0LE ]
Publication DOI: 10.1002/hlca.201400297Journal NLM ID: 2985094RPublisher: Verlag Helvetica Chimica Acta
Correspondence: Zhao QJ <qjzhao
smmu.edu.cn>; Wu QY <wuqysmmu
sohu.com>
Institutions: School of Pharmacy, Yantai University, Yantai, China, Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, China
β-D-GlcpA-(1→2)-[β-D-Xylp-(1→2)-α-D-Manp-(1→3)]-α-D-Manp-(1→3)-α-D-Manp, the repeating unit of the exopolysaccharide from Cryptococcus neoformans serotype D, was synthesized as its 4-methoxyphenyl glycoside. The approach presented here also provides a route to the synthesis of more complex repeating units of glucuronoxylomannan (GXM) of C. neoformans serotypes A-C
synthesis, Cryptococcus neoformans, Glucuronoxylomannan
Structure type: suggested polymer biological repeating unit
Location inside paper: p. 619, Fig. B
Trivial name: glucuronoxylomannan (GXM), glucuronoxylomannan
Compound class: CPS, EPS, O-polysaccharide, O-antigen, cell wall polysaccharide, polysaccharide, glucuronoxylomannan, capsule polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_115136,IEDB_115576,IEDB_130701,IEDB_140116,IEDB_140630,IEDB_144983,IEDB_145668,IEDB_152206,IEDB_164174,IEDB_167188,IEDB_174332,IEDB_2270799,IEDB_423153,IEDB_76933,IEDB_983930,SB_197,SB_44,SB_67,SB_72
Methods: 13C NMR, 1H NMR, TLC, ESI-MS, chemical synthesis, CC, ESI-QTOF-MS
Related record ID(s): 48484, 48486, 48487
NCBI Taxonomy refs (TaxIDs): 37769Reference(s) to other database(s): GTC:G42955PN
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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(later renamed to: Cryptococcus gattii VGI)