Taxonomic group: fungi / Mucoromycota
(Phylum: Mucoromycota)
Organ / tissue: cell wall
NCBI PubMed ID: 30941108Publication DOI: 10.3389/fmicb.2019.00469Journal NLM ID: 101548977Publisher: Lausanne: Frontiers Research Foundation
Correspondence: Sendid B <boualem.sendid
univ-lille.fr>
Institutions: Lille Inflammation Research International Center, UMR 995 Inserm, Fungal Associated Invasive and Inflammatory Diseases, CHU Lille, Lille University, Lille, France, Laboratory of Parasitology and Mycology, Institute of Microbiology, CHU Lille, Lille, France
Invasive fungal infections are some of the most life-threatening infectious diseases in the hospital setting. In industrialized countries, the most common fungal species isolated from immunocompromised patients are Candida and Aspergillus spp. However, the number of infections due to Mucorales spp. is constantly increasing and little is known about the virulence factors of these fungi. The fungal cell wall is an important structure protecting fungi from the environment. A better knowledge of its composition should improve our understanding of host-pathogen interactions. Cell wall molecules are involved in tissue adherence, immune escape strategies, and stimulation of host defenses including phagocytosis and mediators of humoral immunity. The fungal cell wall is also a target of choice for the development of diagnostic or therapeutic tools. The present review discusses our current knowledge on the cell wall structure of Mucorales in terms of the polysaccharides and glyco-enzymes involved in its biosynthesis and degradation, with an emphasis on the missing gaps in our knowledge.
cell wall, polysaccharides, glucuronic acid, Mucorales, glyco-enzymes
Structure type: homopolymer
Location inside paper: Table 1, chitin
Trivial name: chitin
Compound class: O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide, chitin
Contained glycoepitopes: IEDB_135813,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_153212,IEDB_241099,IEDB_423114,IEDB_423150,SB_74,SB_85
Related record ID(s): 40760, 40800, 41831, 42398, 48828, 49501, 111874, 121703, 131817, 139821, 143656, 147987, 149876
NCBI Taxonomy refs (TaxIDs): 4827Reference(s) to other database(s): GTC:G97099AY, CCSD:
46067, CBank-STR:5851, GenDB:KF905651
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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