During the course of screening program for new antitumor antibiotics, three active substances has been isolated which were named kerriamycins A, B and C, respectively, from the culture broth of a streptomycete. These antibiotics inhibit the growth of Gram-positive bacteria and prolong the survival periods of mice bearing Ehrlich ascites carcinoma.
antibiotics, kerriamycins, Streptomyces violaceolatus
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