Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
Publication DOI: 10.1016/j.carres.2003.08.010Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: cwhitfie
uoguelph.ca
Institutions: Department of Microbiology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Extracellular and capsular polysaccharides (EPSs and CPSs) are produced by a wide range of bacteria, including important pathogens of humans, livestock, and plants. These polymers are major surface antigens and serve a variety of roles in virulence, depending on the biology of the producing organism. In addition to their importance in disease, some EPSs also have industrial applications as gelling and emulsifying agents. An understanding of the processes involved in the synthesis and regulation of CPSs and EPSs therefore potentially contributes to an understanding of the disease state, surface expression of protective antigens, and modulation of polymer structure to give defined physical properties. Escherichia coli has provided important model systems for EPS and CPS biosynthesis. Here we describe current knowledge concerning assembly of the Group 1 CPSs of E. coli and the conservation of similar mechanisms in other bacteria
biosynthesis, Escherichia coli, capsular polysaccharide, extracellular polysaccharide, K-antigens, Wzy-dependent assembly
Structure type: polymer chemical repeating unit
Location inside paper: p.2493, fig.1, K-30 antigen
Compound class: CPS, EPS, K-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_136044,IEDB_136906,IEDB_137472,IEDB_140630,IEDB_141794,IEDB_144983,IEDB_151528,IEDB_152206,IEDB_190606,IEDB_423153,IEDB_983930,SB_165,SB_166,SB_187,SB_195,SB_44,SB_67,SB_7,SB_72,SB_88
Comments, role: review
Related record ID(s): 31505, 31506
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G72490SX, GlycomeDB:
678
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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