Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Acinetobacter baumannii [ICD11:
XN8LS 
]
The structure was elucidated in this paperNCBI PubMed ID: 9063458Journal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: School of Chemistry, University of Hull, England, Institute fur Medizinishe Mikrobiologue und Hygiene, Universitat des Saarlandes, Homburg, Germany
A polysaccharide containing D-galactose (Gal), 2-acetamido-2-deoxy-D-galactose (GalNAc), 2-acetamido-2-deoxy-D-glucose (GlcNAc), and 3-deoxy-3-(D-3-hydroxybutyramido)-D-quinovose (Qui3NR) was isolated from lipopolysaccharide (LPS) obtained from cells walls of the reference strain for Acinetobacter baumannii O23. By means of NMR studies, methylation analysis, and chemical degradations, the repeating unit of the polymer was identified as a branched pentasaccharide with the structure 1. The same polymer was apparently also present in LPS of the reference strain for serogroup O12, together with a second polymer based on a branched tetrasaccharide with the structure 2. This second polymer has previously been isolated as the O16 antigen of A. baumannii [Haseley, S.R., Diggle, H.J. & Wilkinson, S. G. (1996) Carbohydr. Res. 293, 259-265] and is probably present as a minor component of the LPS of A. baumannii O11 [Haseley, S.R. & Wilkinson, S.G. (1996) Eur. J. Biochem. 237, 266-271]. [Sequence: see text]
Lipopolysaccharide, lipopolysaccharides, LPS, structure, strain, Acinetobacter, Acinetobacter baumannii, O antigens, reference
Structure type: oligomer
Location inside paper: structure 3
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_130648,IEDB_137340,IEDB_137473,IEDB_1391961,IEDB_141584,IEDB_141807,IEDB_151531,IEDB_885822
Methods: methylation, NMR-2D, partial acid hydrolysis, NMR, Smith degradation, de-N-acylation/deamination
Biological activity: serological studies
Enzymes that release or process the structure: D-hydroxybutyrate dehydrogenase
Related record ID(s): 493, 563
NCBI Taxonomy refs (TaxIDs): 470Reference(s) to other database(s): GTC:G64042AV
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error