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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Acinetobacter [ICD11: XN25B

]

The structure was elucidated in this paper
NCBI PubMed ID: 8774703
Publication DOI: 10.1111/j.1432-1033.1995.899_3.x
Journal NLM ID: 0107600
Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Division of Biochemical Microbiology, Center for Medicine and Biosciences, Research Center Borstel, Germany, Department of Medical Microbiology, Leiden University Hospital, Leiden, The Netherlands

Extraction of dry bacteria of Acinetobacter strain 34 (DNA group 2) or Acinetobacter strain 108 (DNA group 13) by phenol/water yielded a polymer that was identified by means of serological studies and fatty acid analysis as S-form lipopolysaccharide. Degradation of the lipopolysaccharides of strains 34 and 108 in 1% acetic acid and 5% acetic acid, respectively, and gel-permeation chromatography gave the respective O-antigenic polysaccharides, the structures of which were determined, by compositional analysis and NMR spectroscopy of the polysaccharide, as [Sequence: see text] for strain 108, where D-Fucp3NBuOH represents 3-[(R)-3-hydroxybutyramido] -3,6-dideoxy-D-galactose and D-GalpANAc represents 2-acetamido-2-deoxy-D-galacturonic acid. Both structures were specifically recognised in Western blots by polyclonal rabbit antisera and there was no cross-reaction between these two structures.

Lipopolysaccharide, NMR, Acinetobacter, serology, Western blot

Structure type: polymer chemical repeating unit
Location inside paper: p.608
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_130648,IEDB_136906,IEDB_137472,IEDB_137473,IEDB_1391961,IEDB_141582,IEDB_141584,IEDB_141794,IEDB_151528,IEDB_153207,IEDB_153208,IEDB_190606,IEDB_885822,SB_21,SB_25,SB_7

Methods: NMR-2D, NMR, composition analysis
Biological activity: serological data
Comments, role: O-specific polysaccharide, Smith degradation product

Related record ID(s): 5524, 5740, 5741
NCBI Taxonomy refs (TaxIDs): 472
Show glycosyltransferases

There is only one chemically distinct structure:

*C[C@H](O)CO[C@H]1O[C@H](CO)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O*)[C@H]2NC(C)=O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](C)[C@H](O)[C@H](NC(=O)C[C@@H](C)O)[C@H]4O)[C@H]3NC(C)=O)[C@H]2NC(C)=O)[C@H]1O

SVG MW SMILES 3D mol Ionize