Taxonomic group: protista / Euglenozoa
(Phylum: Euglenozoa)
Host organism: (mammal)
Associated disease: animal trypanosomiasis (Nagana disease) [ICD11:
XN9H4 
]
Publication DOI: 10.1080/07328303.2013.831435Journal NLM ID: 8218151Publisher: Marcel Dekker
Correspondence: ben.swarts
cmich.edu
Institutions: Department of Chemistry, Central Michigan University, Mount Pleasant, MI, 48859, USA
Carbohydrate chemists have been remarkably successful at developing methods for the chemical synthesis of glycosylphosphatidylinositols (GPIs), a highly complex and structurally diverse family of glycolipids that anchor proteins to eukaryotic cell surfaces. With the goal of generating new tools for GPI biological research, several groups in this field have recently shifted their attention from narrowly focused target-oriented total synthesis to the development of more versatile synthetic strategies that allow access to a broad variety of GPIs, GPI analogs, and GPI-anchored proteins. These recent efforts are the topic of this review article.
glycolipids, chemical synthesis, glycosylphosphatidylinositol (GPI) anchor
Structure type: oligomer
Location inside paper: p. 281, Fig. 4B, T. congolense GPI-anchor 4
Trivial name: variant surface glycoproteins (VSG) GPI anchor 4
Compound class: GPI-anchor
Contained glycoepitopes: IEDB_120354,IEDB_123890,IEDB_130701,IEDB_135813,IEDB_136044,IEDB_136104,IEDB_137340,IEDB_137472,IEDB_140116,IEDB_141793,IEDB_141794,IEDB_141807,IEDB_141829,IEDB_143632,IEDB_144983,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_176772,IEDB_190606,IEDB_474450,IEDB_983930,SB_136,SB_165,SB_166,SB_187,SB_191,SB_195,SB_196,SB_198,SB_44,SB_67,SB_7,SB_72,SB_88
Synthetic data: chemical
Comments, role: review
NCBI Taxonomy refs (TaxIDs): 5692
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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